KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UAP1
All Species:
17.88
Human Site:
S460
Identified Species:
28.1
UniProt:
Q16222
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16222
NP_003106.3
522
58769
S460
R
S
A
T
N
G
K
S
E
T
I
T
A
D
V
Chimpanzee
Pan troglodytes
XP_001174283
522
58736
S460
R
S
A
T
N
G
K
S
E
T
I
T
A
D
V
Rhesus Macaque
Macaca mulatta
XP_001118199
522
58639
S460
R
S
A
T
N
G
K
S
E
T
I
T
A
D
V
Dog
Lupus familis
XP_849867
522
58787
S460
R
S
A
T
N
G
K
S
E
T
I
T
A
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91YN5
522
58590
S460
R
S
A
T
N
G
K
S
E
A
I
T
A
D
V
Rat
Rattus norvegicus
XP_573497
521
58376
E460
R
A
T
N
G
K
S
E
T
I
T
A
D
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509643
385
43006
H346
I
H
E
P
Q
L
Q
H
H
V
A
Q
K
K
I
Chicken
Gallus gallus
XP_415568
501
55961
P458
S
L
S
G
T
E
D
P
P
A
V
C
E
I
S
Frog
Xenopus laevis
NP_001091348
523
58611
G460
L
Q
T
N
G
V
C
G
A
A
Q
D
H
A
E
Zebra Danio
Brachydanio rerio
Q7ZWD4
505
56395
V464
Q
I
E
D
P
P
A
V
C
E
I
S
P
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609032
520
58196
V480
G
G
I
V
H
G
E
V
C
E
I
S
P
F
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18493
484
53478
A441
R
V
Q
A
K
V
T
A
T
E
K
P
I
Y
L
Sea Urchin
Strong. purpuratus
XP_779933
489
55054
D439
S
R
R
A
H
D
P
D
G
Y
P
V
T
C
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64765
502
55741
A456
L
H
T
R
W
V
I
A
A
G
G
F
L
T
H
Baker's Yeast
Sacchar. cerevisiae
P43123
477
53458
G438
T
S
W
L
E
D
A
G
A
I
V
K
D
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
96.1
N.A.
93.4
93.3
N.A.
48.4
58.8
73.6
56.7
N.A.
50.3
N.A.
36.4
57.8
Protein Similarity:
100
100
99.2
98.8
N.A.
96.9
96.5
N.A.
61.2
72
85.4
71.8
N.A.
69.7
N.A.
55.3
73.1
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
0
0
0
13.3
N.A.
20
N.A.
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
13.3
13.3
0
26.6
N.A.
40
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
34
14
0
0
14
14
20
20
7
7
34
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
14
0
0
7
0
7
0
% C
% Asp:
0
0
0
7
0
14
7
7
0
0
0
7
14
34
0
% D
% Glu:
0
0
14
0
7
7
7
7
34
20
0
0
7
0
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% F
% Gly:
7
7
0
7
14
40
0
14
7
7
7
0
0
7
0
% G
% His:
0
14
0
0
14
0
0
7
7
0
0
0
7
0
7
% H
% Ile:
7
7
7
0
0
0
7
0
0
14
47
0
7
7
7
% I
% Lys:
0
0
0
0
7
7
34
0
0
0
7
7
7
7
0
% K
% Leu:
14
7
0
7
0
7
0
0
0
0
0
0
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
34
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
7
7
7
7
7
7
0
7
7
14
0
0
% P
% Gln:
7
7
7
0
7
0
7
0
0
0
7
7
0
0
0
% Q
% Arg:
47
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
14
40
7
0
0
0
7
34
0
0
0
14
0
0
7
% S
% Thr:
7
0
20
34
7
0
7
0
14
27
7
34
7
7
0
% T
% Val:
0
7
0
7
0
20
0
14
0
7
14
7
0
7
54
% V
% Trp:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _