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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT7
All Species:
4.55
Human Site:
Y41
Identified Species:
9.09
UniProt:
Q16181
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16181
NP_001011553.2
437
50680
Y41
A
N
L
P
N
Q
V
Y
R
K
S
V
K
R
G
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
K43
Q
V
Y
R
K
S
V
K
R
G
F
E
F
T
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532516
396
46160
I46
Y
P
G
P
S
H
R
I
K
K
T
V
Q
V
E
Cat
Felis silvestris
Mouse
Mus musculus
O55131
436
50531
R41
N
L
P
N
Q
V
Y
R
K
S
V
K
R
G
F
Rat
Rattus norvegicus
Q9WVC0
436
50489
R41
N
L
P
N
Q
V
Y
R
K
S
V
K
R
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMH1
349
40206
V41
G
F
E
F
T
L
M
V
V
G
E
S
G
L
G
Frog
Xenopus laevis
Q9DE33
356
40909
V41
G
F
E
F
T
L
M
V
V
G
E
S
G
L
G
Zebra Danio
Brachydanio rerio
A4FUM1
423
49080
F41
S
K
S
V
S
Q
G
F
S
F
N
I
L
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40797
539
60125
R134
N
L
P
N
Q
V
Y
R
K
A
V
K
R
G
F
Honey Bee
Apis mellifera
XP_001121636
646
72341
Y258
A
N
L
P
N
Q
V
Y
R
K
A
V
K
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175696
462
53661
K73
Q
R
I
K
K
T
V
K
V
E
T
S
Q
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
H110
A
N
L
P
K
Q
W
H
R
R
S
I
K
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
89
N.A.
98.8
98.8
N.A.
N.A.
49.2
49.2
41.1
N.A.
54.9
48.4
N.A.
66.2
Protein Similarity:
100
99
N.A.
89.6
N.A.
99
99
N.A.
N.A.
64.5
64.7
60.6
N.A.
67.5
57.4
N.A.
77.4
P-Site Identity:
100
13.3
N.A.
20
N.A.
0
0
N.A.
N.A.
6.6
6.6
6.6
N.A.
0
86.6
N.A.
6.6
P-Site Similarity:
100
13.3
N.A.
46.6
N.A.
13.3
13.3
N.A.
N.A.
13.3
13.3
40
N.A.
13.3
100
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
0
0
0
9
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
17
0
0
0
0
0
0
9
17
9
0
0
9
% E
% Phe:
0
17
0
17
0
0
0
9
0
9
9
0
9
0
25
% F
% Gly:
17
0
9
0
0
0
9
0
0
25
0
0
17
25
42
% G
% His:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
0
0
0
17
0
0
0
% I
% Lys:
0
9
0
9
25
0
0
17
34
25
0
25
25
9
0
% K
% Leu:
0
25
25
0
0
17
0
0
0
0
0
0
9
17
9
% L
% Met:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
25
25
0
25
17
0
0
0
0
0
9
0
0
9
9
% N
% Pro:
0
9
25
34
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
17
0
0
0
25
34
0
0
0
0
0
0
17
0
0
% Q
% Arg:
0
9
0
9
0
0
9
25
34
9
0
0
25
9
0
% R
% Ser:
9
0
9
0
17
9
0
0
9
17
17
25
0
0
0
% S
% Thr:
0
0
0
0
17
9
0
0
0
0
17
0
0
9
0
% T
% Val:
0
9
0
9
0
25
34
17
25
0
25
25
0
9
9
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
25
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _