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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT7
All Species:
36.97
Human Site:
S375
Identified Species:
73.94
UniProt:
Q16181
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16181
NP_001011553.2
437
50680
S375
K
V
Q
K
L
K
D
S
E
A
E
L
Q
R
R
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
S372
K
V
Q
K
L
K
D
S
E
A
E
L
Q
R
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532516
396
46160
S334
K
V
Q
K
L
K
D
S
E
A
E
L
Q
R
R
Cat
Felis silvestris
Mouse
Mus musculus
O55131
436
50531
S374
K
V
Q
K
L
K
D
S
E
A
E
L
Q
R
R
Rat
Rattus norvegicus
Q9WVC0
436
50489
S374
K
V
Q
K
L
K
D
S
E
A
E
L
Q
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMH1
349
40206
K324
K
D
R
I
L
Q
Q
K
E
A
E
L
R
R
M
Frog
Xenopus laevis
Q9DE33
356
40909
K326
K
D
Q
I
L
Q
E
K
E
A
E
L
R
R
M
Zebra Danio
Brachydanio rerio
A4FUM1
423
49080
T353
F
V
N
K
V
K
E
T
E
A
E
L
K
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40797
539
60125
S466
K
M
Q
K
L
R
D
S
E
L
E
L
A
R
R
Honey Bee
Apis mellifera
XP_001121636
646
72341
S588
K
K
Q
K
L
K
D
S
E
A
D
L
Q
R
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175696
462
53661
S384
K
Q
K
G
L
E
D
S
E
A
D
M
Q
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
S466
K
E
K
K
L
Q
K
S
E
T
E
L
F
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
89
N.A.
98.8
98.8
N.A.
N.A.
49.2
49.2
41.1
N.A.
54.9
48.4
N.A.
66.2
Protein Similarity:
100
99
N.A.
89.6
N.A.
99
99
N.A.
N.A.
64.5
64.7
60.6
N.A.
67.5
57.4
N.A.
77.4
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
46.6
53.3
46.6
N.A.
73.3
86.6
N.A.
53.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
66.6
73.3
80
N.A.
86.6
93.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
84
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
0
67
0
0
0
17
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
17
0
100
0
84
0
0
9
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
92
9
17
75
0
59
9
17
0
0
0
0
9
9
9
% K
% Leu:
0
0
0
0
92
0
0
0
0
9
0
92
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
17
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
67
0
0
25
9
0
0
0
0
0
59
0
0
% Q
% Arg:
0
0
9
0
0
9
0
0
0
0
0
0
17
75
75
% R
% Ser:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% T
% Val:
0
50
0
0
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _