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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP2
All Species:
30.3
Human Site:
Y99
Identified Species:
47.62
UniProt:
Q15833
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15833
NP_008880
593
66439
Y99
Q
G
T
P
T
F
T
Y
K
A
A
H
I
F
F
Chimpanzee
Pan troglodytes
XP_001153467
595
66736
Y99
Q
G
T
P
T
F
T
Y
K
A
A
H
I
F
F
Rhesus Macaque
Macaca mulatta
XP_001097163
644
70907
R132
R
G
R
D
Q
G
P
R
G
G
V
H
V
G
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
Y99
Q
G
T
P
T
F
T
Y
K
A
A
H
I
F
F
Rat
Rattus norvegicus
Q62753
594
66677
Y99
Q
G
T
P
T
F
T
Y
K
A
A
H
I
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
D98
F
F
T
D
S
C
P
D
A
L
F
N
E
L
V
Chicken
Gallus gallus
Q6R748
594
67454
Y99
K
D
P
P
T
S
K
Y
R
A
A
H
V
F
F
Frog
Xenopus laevis
NP_001093335
595
67691
Y99
K
D
P
P
S
S
K
Y
R
A
A
H
V
F
F
Zebra Danio
Brachydanio rerio
NP_998454
595
67030
Y98
F
R
E
T
A
F
T
Y
K
A
A
H
V
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
Y110
E
N
P
A
R
P
M
Y
R
Y
A
H
V
F
F
Honey Bee
Apis mellifera
XP_396375
585
66573
Y99
S
N
P
T
R
T
S
Y
K
V
A
H
V
Y
F
Nematode Worm
Caenorhab. elegans
P34815
673
76715
Y179
D
Y
C
A
R
N
L
Y
K
C
A
H
V
F
F
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
A99
N
S
L
Q
Y
K
V
A
H
I
F
F
T
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
K114
T
G
K
S
P
L
Y
K
K
A
F
V
F
F
S
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
F115
T
N
P
I
F
Q
F
F
Q
S
K
R
Y
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
72.5
N.A.
N.A.
94.9
94.4
N.A.
61.3
63.6
62.3
68
N.A.
56.1
56.3
47.8
52.6
Protein Similarity:
100
99.1
72.9
N.A.
N.A.
97.1
97.1
N.A.
78.2
80.3
80
82.1
N.A.
72.6
74.5
64
72.3
P-Site Identity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
6.6
53.3
46.6
60
N.A.
33.3
33.3
40
0
P-Site Similarity:
100
100
26.6
N.A.
N.A.
100
100
N.A.
20
73.3
73.3
66.6
N.A.
53.3
53.3
46.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
7
0
0
7
7
54
67
0
0
0
7
% A
% Cys:
0
0
7
0
0
7
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
14
0
14
0
0
0
7
0
0
0
0
0
0
7
% D
% Glu:
7
0
7
0
0
0
0
0
0
0
0
0
7
7
0
% E
% Phe:
14
7
0
0
7
34
7
7
0
0
20
7
7
67
67
% F
% Gly:
0
40
0
0
0
7
0
0
7
7
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
74
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
7
0
0
27
7
0
% I
% Lys:
14
0
7
0
0
7
14
7
54
0
7
0
0
0
0
% K
% Leu:
0
0
7
0
0
7
7
0
0
7
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
7
20
0
0
0
7
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
34
40
7
7
14
0
0
0
0
0
0
0
0
% P
% Gln:
27
0
0
7
7
7
0
0
7
0
0
0
0
0
0
% Q
% Arg:
7
7
7
0
20
0
0
7
20
0
0
7
0
0
0
% R
% Ser:
7
7
0
7
14
14
7
0
0
7
0
0
0
0
7
% S
% Thr:
14
0
34
14
34
7
34
0
0
0
0
0
7
0
7
% T
% Val:
0
0
0
0
0
0
7
0
0
7
7
7
47
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
7
0
7
67
0
7
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _