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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP2
All Species:
19.39
Human Site:
Y157
Identified Species:
30.48
UniProt:
Q15833
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15833
NP_008880
593
66439
Y157
P
H
S
T
Y
N
L
Y
C
P
F
R
A
E
E
Chimpanzee
Pan troglodytes
XP_001153467
595
66736
N157
D
A
P
H
S
T
Y
N
L
Y
C
P
F
X
A
Rhesus Macaque
Macaca mulatta
XP_001097163
644
70907
K190
V
K
K
D
G
E
W
K
V
L
I
M
D
H
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
Y157
P
H
S
T
Y
N
L
Y
C
P
F
R
A
G
E
Rat
Rattus norvegicus
Q62753
594
66677
Y157
P
H
S
T
Y
N
L
Y
C
P
F
R
A
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
E156
Q
M
K
N
P
I
L
E
R
L
A
E
Q
I
A
Chicken
Gallus gallus
Q6R748
594
67454
Y157
A
D
S
F
Q
S
F
Y
S
P
H
K
A
Q
M
Frog
Xenopus laevis
NP_001093335
595
67691
Y157
P
D
S
F
H
S
F
Y
S
P
H
K
A
Q
M
Zebra Danio
Brachydanio rerio
NP_998454
595
67030
Y156
P
S
S
F
H
A
F
Y
S
P
T
Q
T
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
Y168
P
D
T
F
Q
C
L
Y
S
P
A
F
A
S
I
Honey Bee
Apis mellifera
XP_396375
585
66573
Y157
A
E
T
F
A
C
F
Y
N
A
S
F
S
N
L
Nematode Worm
Caenorhab. elegans
P34815
673
76715
Y237
P
D
T
F
F
L
Y
Y
N
A
Q
K
Q
G
G
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
G157
F
N
V
F
Y
N
P
G
R
G
Q
S
R
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
F172
E
N
A
L
E
E
L
F
C
D
D
E
N
H
Q
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
G173
T
N
V
R
K
I
V
G
S
L
V
S
L
C
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
72.5
N.A.
N.A.
94.9
94.4
N.A.
61.3
63.6
62.3
68
N.A.
56.1
56.3
47.8
52.6
Protein Similarity:
100
99.1
72.9
N.A.
N.A.
97.1
97.1
N.A.
78.2
80.3
80
82.1
N.A.
72.6
74.5
64
72.3
P-Site Identity:
100
0
0
N.A.
N.A.
93.3
93.3
N.A.
6.6
26.6
33.3
26.6
N.A.
33.3
6.6
13.3
13.3
P-Site Similarity:
100
0
0
N.A.
N.A.
93.3
93.3
N.A.
6.6
46.6
60
40
N.A.
40
20
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
0
7
7
0
0
0
14
14
0
40
0
14
% A
% Cys:
0
0
0
0
0
14
0
0
27
0
7
0
0
7
0
% C
% Asp:
7
27
0
7
0
0
0
0
0
7
7
0
7
0
0
% D
% Glu:
7
7
0
0
7
14
0
7
0
0
0
14
0
7
20
% E
% Phe:
7
0
0
47
7
0
27
7
0
0
20
14
7
0
0
% F
% Gly:
0
0
0
0
7
0
0
14
0
7
0
0
0
20
7
% G
% His:
0
20
0
7
14
0
0
0
0
0
14
0
0
14
0
% H
% Ile:
0
0
0
0
0
14
0
0
0
0
7
0
0
7
7
% I
% Lys:
0
7
14
0
7
0
0
7
0
0
0
20
0
0
0
% K
% Leu:
0
0
0
7
0
7
40
0
7
20
0
0
7
0
14
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
20
% M
% Asn:
0
20
0
7
0
27
0
7
14
0
0
0
7
14
0
% N
% Pro:
47
0
7
0
7
0
7
0
0
47
0
7
0
7
7
% P
% Gln:
7
0
0
0
14
0
0
0
0
0
14
7
14
14
7
% Q
% Arg:
0
0
0
7
0
0
0
0
14
0
0
20
7
0
0
% R
% Ser:
0
7
40
0
7
14
0
0
34
0
7
14
7
7
0
% S
% Thr:
7
0
20
20
0
7
0
0
0
0
7
0
7
0
0
% T
% Val:
7
0
14
0
0
0
7
0
7
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
27
0
14
60
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _