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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP2
All Species:
13.64
Human Site:
T94
Identified Species:
21.43
UniProt:
Q15833
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15833
NP_008880
593
66439
T94
L
I
K
D
F
Q
G
T
P
T
F
T
Y
K
A
Chimpanzee
Pan troglodytes
XP_001153467
595
66736
T94
L
I
K
D
F
Q
G
T
P
T
F
T
Y
K
A
Rhesus Macaque
Macaca mulatta
XP_001097163
644
70907
R127
R
G
Q
V
R
R
G
R
D
Q
G
P
R
G
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
T94
L
I
A
D
F
Q
G
T
P
T
F
T
Y
K
A
Rat
Rattus norvegicus
Q62753
594
66677
T94
L
I
A
D
F
Q
G
T
P
T
F
T
Y
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
T93
R
A
A
H
V
F
F
T
D
S
C
P
D
A
L
Chicken
Gallus gallus
Q6R748
594
67454
P94
L
I
S
D
F
K
D
P
P
T
S
K
Y
R
A
Frog
Xenopus laevis
NP_001093335
595
67691
P94
L
I
S
D
F
K
D
P
P
S
S
K
Y
R
A
Zebra Danio
Brachydanio rerio
NP_998454
595
67030
E93
A
L
I
A
D
F
R
E
T
A
F
T
Y
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
P105
L
I
R
D
F
E
N
P
A
R
P
M
Y
R
Y
Honey Bee
Apis mellifera
XP_396375
585
66573
P94
L
I
E
D
F
S
N
P
T
R
T
S
Y
K
V
Nematode Worm
Caenorhab. elegans
P34815
673
76715
C174
D
K
L
I
Q
D
Y
C
A
R
N
L
Y
K
C
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
L94
D
F
K
D
I
N
S
L
Q
Y
K
V
A
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
K109
F
L
S
D
M
T
G
K
S
P
L
Y
K
K
A
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
P110
F
L
P
G
L
T
N
P
I
F
Q
F
F
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
72.5
N.A.
N.A.
94.9
94.4
N.A.
61.3
63.6
62.3
68
N.A.
56.1
56.3
47.8
52.6
Protein Similarity:
100
99.1
72.9
N.A.
N.A.
97.1
97.1
N.A.
78.2
80.3
80
82.1
N.A.
72.6
74.5
64
72.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
93.3
93.3
N.A.
6.6
53.3
46.6
33.3
N.A.
33.3
40
13.3
13.3
P-Site Similarity:
100
100
20
N.A.
N.A.
93.3
93.3
N.A.
13.3
66.6
66.6
40
N.A.
53.3
53.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
20
7
0
0
0
0
14
7
0
0
7
7
54
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
7
% C
% Asp:
14
0
0
67
7
7
14
0
14
0
0
0
7
0
0
% D
% Glu:
0
0
7
0
0
7
0
7
0
0
0
0
0
0
0
% E
% Phe:
14
7
0
0
54
14
7
0
0
7
34
7
7
0
0
% F
% Gly:
0
7
0
7
0
0
40
0
0
0
7
0
0
7
7
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
54
7
7
7
0
0
0
7
0
0
0
0
0
7
% I
% Lys:
0
7
20
0
0
14
0
7
0
0
7
14
7
54
0
% K
% Leu:
54
20
7
0
7
0
0
7
0
0
7
7
0
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
7
20
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
34
40
7
7
14
0
0
0
% P
% Gln:
0
0
7
0
7
27
0
0
7
7
7
0
0
7
0
% Q
% Arg:
14
0
7
0
7
7
7
7
0
20
0
0
7
20
0
% R
% Ser:
0
0
20
0
0
7
7
0
7
14
14
7
0
0
7
% S
% Thr:
0
0
0
0
0
14
0
34
14
34
7
34
0
0
0
% T
% Val:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
7
0
7
67
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _