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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STXBP2 All Species: 34.85
Human Site: S70 Identified Species: 54.76
UniProt: Q15833 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15833 NP_008880 593 66439 S70 K R R E P I P S L E A I Y L L
Chimpanzee Pan troglodytes XP_001153467 595 66736 S70 K R R E P I P S L E A I Y L L
Rhesus Macaque Macaca mulatta XP_001097163 644 70907 S103 R R R T C L S S P P G T Q L P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q64324 593 66339 S70 K R R E P I P S L E A I Y L L
Rat Rattus norvegicus Q62753 594 66677 S70 K R R E P I P S L E A I Y L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508183 589 67400 S69 L I T P S E K S V H S L I S D
Chicken Gallus gallus Q6R748 594 67454 S70 K R R E P L P S L E A V Y L I
Frog Xenopus laevis NP_001093335 595 67691 S70 K R R E P L P S L E A V Y L I
Zebra Danio Brachydanio rerio NP_998454 595 67030 P69 S K R R E P I P S L E A I Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07327 597 67832 T81 K K R E P L P T M D A I Y L I
Honey Bee Apis mellifera XP_396375 585 66573 T70 K K R E P L P T M E A I Y L I
Nematode Worm Caenorhab. elegans P34815 673 76715 L150 L N K R R E P L P T L E A I Y
Sea Urchin Strong. purpuratus NP_999834 593 68046 G70 E P L K G L E G V Y I I Q P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SZ77 662 75299 A85 K H R Q P M T A M E V I Y F I
Baker's Yeast Sacchar. cerevisiae P30619 724 83462 D86 K Y N I N C I D A D F M V R P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 72.5 N.A. N.A. 94.9 94.4 N.A. 61.3 63.6 62.3 68 N.A. 56.1 56.3 47.8 52.6
Protein Similarity: 100 99.1 72.9 N.A. N.A. 97.1 97.1 N.A. 78.2 80.3 80 82.1 N.A. 72.6 74.5 64 72.3
P-Site Identity: 100 100 26.6 N.A. N.A. 100 100 N.A. 6.6 80 80 13.3 N.A. 60 66.6 6.6 6.6
P-Site Similarity: 100 100 40 N.A. N.A. 100 100 N.A. 26.6 100 100 20 N.A. 100 100 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. 28.8 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. 49.7 42.5 N.A.
P-Site Identity: N.A. N.A. N.A. 40 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 7 7 0 54 7 7 0 0 % A
% Cys: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 14 0 0 0 0 7 % D
% Glu: 7 0 0 54 7 14 7 0 0 54 7 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % F
% Gly: 0 0 0 0 7 0 0 7 0 0 7 0 0 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 7 0 7 0 27 14 0 0 0 7 54 14 7 34 % I
% Lys: 67 20 7 7 0 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 14 0 7 0 0 40 0 7 40 7 7 7 0 60 34 % L
% Met: 0 0 0 0 0 7 0 0 20 0 0 7 0 0 0 % M
% Asn: 0 7 7 0 7 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 7 0 7 60 7 60 7 14 7 0 0 0 7 14 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 14 0 0 % Q
% Arg: 7 47 74 14 7 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 7 0 0 0 7 0 7 54 7 0 7 0 0 7 0 % S
% Thr: 0 0 7 7 0 0 7 14 0 7 0 7 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 14 0 7 14 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 7 0 0 60 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _