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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP2
All Species:
36.36
Human Site:
S513
Identified Species:
57.14
UniProt:
Q15833
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15833
NP_008880
593
66439
S513
A
S
S
Q
A
A
V
S
A
R
F
G
H
W
H
Chimpanzee
Pan troglodytes
XP_001153467
595
66736
S515
A
S
S
Q
A
A
V
S
A
R
F
G
H
W
H
Rhesus Macaque
Macaca mulatta
XP_001097163
644
70907
S546
E
G
E
K
I
K
D
S
M
K
L
I
V
P
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
S513
P
S
S
Q
A
A
V
S
A
R
F
G
H
W
H
Rat
Rattus norvegicus
Q62753
594
66677
S513
S
S
S
Q
A
A
V
S
S
A
R
F
G
H
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
S502
S
F
S
T
T
A
V
S
A
R
Y
G
H
W
H
Chicken
Gallus gallus
Q6R748
594
67454
S516
S
F
S
T
T
A
V
S
A
R
Y
G
H
W
H
Frog
Xenopus laevis
NP_001093335
595
67691
S517
S
F
S
T
T
A
V
S
A
R
Y
G
H
W
H
Zebra Danio
Brachydanio rerio
NP_998454
595
67030
S515
T
T
T
A
T
T
V
S
S
A
R
F
G
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
S524
T
N
Y
H
A
P
T
S
A
R
Y
G
H
W
H
Honey Bee
Apis mellifera
XP_396375
585
66573
S514
S
G
Y
H
A
P
T
S
A
R
Y
G
H
W
H
Nematode Worm
Caenorhab. elegans
P34815
673
76715
S597
Q
G
Y
R
A
P
A
S
A
R
Y
G
Q
W
H
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
S519
T
G
S
S
G
P
K
S
A
R
Y
G
N
W
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
P557
F
Y
S
G
S
L
S
P
S
A
S
P
V
L
P
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
L567
S
A
N
S
S
S
S
L
R
N
P
R
H
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
72.5
N.A.
N.A.
94.9
94.4
N.A.
61.3
63.6
62.3
68
N.A.
56.1
56.3
47.8
52.6
Protein Similarity:
100
99.1
72.9
N.A.
N.A.
97.1
97.1
N.A.
78.2
80.3
80
82.1
N.A.
72.6
74.5
64
72.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
93.3
46.6
N.A.
66.6
66.6
66.6
13.3
N.A.
53.3
53.3
46.6
46.6
P-Site Similarity:
100
100
20
N.A.
N.A.
93.3
60
N.A.
80
80
80
33.3
N.A.
66.6
66.6
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
7
47
47
7
0
67
20
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
20
0
0
0
0
0
0
0
0
20
14
0
0
0
% F
% Gly:
0
27
0
7
7
0
0
0
0
0
0
67
14
0
0
% G
% His:
0
0
0
14
0
0
0
0
0
0
0
0
60
14
67
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
7
0
7
7
0
0
7
0
0
0
7
0
% K
% Leu:
0
0
0
0
0
7
0
7
0
0
7
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
0
0
0
0
7
0
0
7
0
0
% N
% Pro:
7
0
0
0
0
27
0
7
0
0
7
7
0
7
7
% P
% Gln:
7
0
0
27
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
7
67
14
7
0
0
0
% R
% Ser:
40
27
60
14
14
7
14
87
20
0
7
0
0
0
0
% S
% Thr:
20
7
7
20
27
7
14
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
54
0
0
0
0
0
14
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
14
% W
% Tyr:
0
7
20
0
0
0
0
0
0
0
47
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _