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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP2
All Species:
17.58
Human Site:
S313
Identified Species:
27.62
UniProt:
Q15833
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15833
NP_008880
593
66439
S313
L
L
R
T
F
C
E
S
K
R
L
T
T
D
K
Chimpanzee
Pan troglodytes
XP_001153467
595
66736
S315
L
L
R
T
F
C
E
S
K
R
L
T
T
D
K
Rhesus Macaque
Macaca mulatta
XP_001097163
644
70907
L340
L
A
Q
Q
I
A
T
L
C
A
T
L
Q
E
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
S313
L
L
K
T
F
C
E
S
K
R
L
T
T
D
K
Rat
Rattus norvegicus
Q62753
594
66677
S313
L
L
K
T
F
C
E
S
K
R
L
T
T
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
K300
L
K
D
F
S
S
S
K
R
M
N
T
G
E
K
Chicken
Gallus gallus
Q6R748
594
67454
K314
L
K
E
F
S
S
S
K
R
M
N
T
G
D
K
Frog
Xenopus laevis
NP_001093335
595
67691
R315
K
D
F
S
A
S
K
R
M
N
T
G
D
K
V
Zebra Danio
Brachydanio rerio
NP_998454
595
67030
S314
L
L
R
V
F
C
D
S
K
R
M
N
T
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
K323
L
K
K
F
T
D
S
K
R
M
G
S
A
D
K
Honey Bee
Apis mellifera
XP_396375
585
66573
K311
L
K
K
F
T
E
S
K
R
M
P
Q
G
D
K
Nematode Worm
Caenorhab. elegans
P34815
673
76715
G395
K
K
F
S
E
S
K
G
N
K
G
T
M
D
S
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
K311
K
D
F
A
Q
G
K
K
M
G
S
G
G
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
H348
N
K
A
A
Q
L
K
H
S
S
K
D
F
G
D
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
K335
R
I
K
E
L
I
A
K
N
P
L
L
V
D
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
72.5
N.A.
N.A.
94.9
94.4
N.A.
61.3
63.6
62.3
68
N.A.
56.1
56.3
47.8
52.6
Protein Similarity:
100
99.1
72.9
N.A.
N.A.
97.1
97.1
N.A.
78.2
80.3
80
82.1
N.A.
72.6
74.5
64
72.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
93.3
93.3
N.A.
20
26.6
0
73.3
N.A.
20
20
13.3
13.3
P-Site Similarity:
100
100
20
N.A.
N.A.
100
100
N.A.
33.3
33.3
13.3
86.6
N.A.
40
33.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
14
7
7
7
0
0
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
34
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
14
7
0
0
7
7
0
0
0
0
7
7
74
7
% D
% Glu:
0
0
7
7
7
7
27
0
0
0
0
0
0
14
0
% E
% Phe:
0
0
20
27
34
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
7
0
7
0
7
14
14
27
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
40
34
0
0
0
27
40
34
7
7
0
0
7
67
% K
% Leu:
67
34
0
0
7
7
0
7
0
0
34
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
14
27
7
0
7
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
14
7
14
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% P
% Gln:
0
0
7
7
14
0
0
0
0
0
0
7
7
0
0
% Q
% Arg:
7
0
20
0
0
0
0
7
27
34
0
0
0
0
7
% R
% Ser:
0
0
0
14
14
27
27
34
7
7
7
7
0
0
7
% S
% Thr:
0
0
0
27
14
0
7
0
0
0
14
47
34
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _