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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP2
All Species:
40
Human Site:
S218
Identified Species:
62.86
UniProt:
Q15833
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15833
NP_008880
593
66439
S218
A
F
K
A
D
T
P
S
L
G
E
G
P
E
K
Chimpanzee
Pan troglodytes
XP_001153467
595
66736
S220
A
F
K
A
D
T
P
S
L
G
E
G
P
E
K
Rhesus Macaque
Macaca mulatta
XP_001097163
644
70907
A250
K
S
V
Q
A
L
I
A
D
F
R
G
T
P
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
S218
A
F
K
A
D
T
P
S
L
G
E
G
P
E
K
Rat
Rattus norvegicus
Q62753
594
66677
S218
A
F
K
A
D
T
P
S
L
G
E
G
P
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
L216
P
D
K
A
R
S
Q
L
L
I
L
D
R
G
F
Chicken
Gallus gallus
Q6R748
594
67454
T218
A
Y
K
A
D
D
P
T
M
G
E
G
P
D
K
Frog
Xenopus laevis
NP_001093335
595
67691
T218
A
Y
K
A
D
D
P
T
M
G
E
G
P
D
K
Zebra Danio
Brachydanio rerio
NP_998454
595
67030
R219
A
H
K
A
D
N
P
R
M
G
E
G
T
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
T229
A
Y
K
A
D
D
A
T
M
G
E
G
P
E
K
Honey Bee
Apis mellifera
XP_396375
585
66573
T218
A
Y
K
A
D
E
P
T
M
G
E
G
P
E
K
Nematode Worm
Caenorhab. elegans
P34815
673
76715
S298
A
Y
K
A
D
D
P
S
M
G
E
G
A
D
K
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
S215
A
Y
K
A
D
D
P
S
M
G
E
G
P
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
T243
C
L
A
R
Y
K
Q
T
I
E
D
F
P
Q
T
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
F235
Y
A
R
N
N
P
D
F
P
P
Q
N
T
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
72.5
N.A.
N.A.
94.9
94.4
N.A.
61.3
63.6
62.3
68
N.A.
56.1
56.3
47.8
52.6
Protein Similarity:
100
99.1
72.9
N.A.
N.A.
97.1
97.1
N.A.
78.2
80.3
80
82.1
N.A.
72.6
74.5
64
72.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
20
66.6
66.6
60
N.A.
66.6
73.3
66.6
80
P-Site Similarity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
26.6
93.3
93.3
73.3
N.A.
86.6
93.3
86.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
74
7
7
80
7
0
7
7
0
0
0
0
7
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
74
34
7
0
7
0
7
7
0
27
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
7
74
0
0
54
0
% E
% Phe:
0
27
0
0
0
0
0
7
0
7
0
7
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
0
74
0
80
0
7
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
7
7
0
0
0
0
0
% I
% Lys:
7
0
80
0
0
7
0
0
0
0
0
0
0
0
74
% K
% Leu:
0
7
0
0
0
7
0
7
34
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
7
0
0
0
0
0
7
0
0
0
% N
% Pro:
7
0
0
0
0
7
67
0
7
7
0
0
67
7
0
% P
% Gln:
0
0
0
7
0
0
14
0
0
0
7
0
0
7
0
% Q
% Arg:
0
0
7
7
7
0
0
7
0
0
7
0
7
0
7
% R
% Ser:
0
7
0
0
0
7
0
40
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
27
0
34
0
0
0
0
20
0
14
% T
% Val:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
40
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _