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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP2
All Species:
21.82
Human Site:
S21
Identified Species:
34.29
UniProt:
Q15833
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15833
NP_008880
593
66439
S21
I
L
S
G
V
I
R
S
V
K
K
D
G
E
W
Chimpanzee
Pan troglodytes
XP_001153467
595
66736
S21
I
L
S
G
V
I
R
S
V
K
K
D
G
E
W
Rhesus Macaque
Macaca mulatta
XP_001097163
644
70907
S36
D
V
T
K
G
L
S
S
V
P
T
V
G
E
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
S21
I
L
S
G
V
I
R
S
V
K
K
D
G
E
W
Rat
Rattus norvegicus
Q62753
594
66677
S21
I
L
S
G
V
I
R
S
V
K
K
D
G
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
Q21
W
K
V
L
V
V
D
Q
L
S
M
R
M
L
S
Chicken
Gallus gallus
Q6R748
594
67454
K21
I
M
H
D
V
I
K
K
V
K
K
K
G
E
W
Frog
Xenopus laevis
NP_001093335
595
67691
K21
I
M
H
D
V
I
R
K
V
K
K
K
G
E
W
Zebra Danio
Brachydanio rerio
NP_998454
595
67030
S21
I
L
S
G
V
I
K
S
V
K
K
D
G
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
A31
K
K
Q
G
V
T
S
A
A
G
A
G
G
M
E
Honey Bee
Apis mellifera
XP_396375
585
66573
T21
E
V
I
K
Q
K
K
T
G
S
S
G
V
Q
W
Nematode Worm
Caenorhab. elegans
P34815
673
76715
P100
L
L
N
D
V
I
R
P
L
K
K
G
D
G
R
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
R22
V
I
I
P
L
R
K
R
K
C
Q
N
V
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
P33
L
L
C
E
M
L
R
P
E
R
N
G
S
S
K
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
F27
E
T
K
N
N
L
K
F
L
I
I
D
K
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
72.5
N.A.
N.A.
94.9
94.4
N.A.
61.3
63.6
62.3
68
N.A.
56.1
56.3
47.8
52.6
Protein Similarity:
100
99.1
72.9
N.A.
N.A.
97.1
97.1
N.A.
78.2
80.3
80
82.1
N.A.
72.6
74.5
64
72.3
P-Site Identity:
100
100
26.6
N.A.
N.A.
100
100
N.A.
6.6
60
66.6
86.6
N.A.
20
6.6
40
0
P-Site Similarity:
100
100
46.6
N.A.
N.A.
100
100
N.A.
20
73.3
73.3
100
N.A.
26.6
33.3
60
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
42.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
7
0
7
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
0
20
0
0
7
0
0
0
0
40
7
7
0
% D
% Glu:
14
0
0
7
0
0
0
0
7
0
0
0
0
47
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
40
7
0
0
0
7
7
0
27
60
7
7
% G
% His:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
7
14
0
0
54
0
0
0
7
7
0
0
0
0
% I
% Lys:
7
14
7
14
0
7
34
14
7
54
54
14
7
0
7
% K
% Leu:
14
47
0
7
7
20
0
0
20
0
0
0
0
14
0
% L
% Met:
0
14
0
0
7
0
0
0
0
0
7
0
7
7
0
% M
% Asn:
0
0
7
7
7
0
0
0
0
0
7
7
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
14
0
7
0
0
0
0
0
% P
% Gln:
0
0
7
0
7
0
0
7
0
0
7
0
0
7
0
% Q
% Arg:
0
0
0
0
0
7
47
7
0
7
0
7
0
0
7
% R
% Ser:
0
0
34
0
0
0
14
40
0
14
7
0
7
7
7
% S
% Thr:
0
7
7
0
0
7
0
7
0
0
7
0
0
7
0
% T
% Val:
7
14
7
0
67
7
0
0
54
0
0
7
14
0
14
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _