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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA6
All Species:
33.94
Human Site:
Y227
Identified Species:
67.88
UniProt:
Q15825
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15825
NP_004189.1
494
56898
Y227
Y
N
C
C
E
E
I
Y
T
D
I
T
Y
S
F
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
Y227
Y
N
C
C
E
E
I
Y
T
D
I
T
Y
S
F
Rhesus Macaque
Macaca mulatta
XP_001099152
494
57084
Y227
Y
N
C
C
E
E
I
Y
T
D
I
T
Y
S
F
Dog
Lupus familis
XP_539951
483
56068
F223
Y
T
D
I
T
Y
S
F
Y
I
R
R
L
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0W9
494
56789
Y227
Y
N
C
C
E
E
I
Y
T
D
I
T
Y
S
F
Rat
Rattus norvegicus
P43143
493
56929
Y227
Y
N
C
C
E
E
I
Y
T
D
I
T
Y
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509745
552
63776
Y244
Y
N
C
C
E
E
I
Y
T
D
I
T
Y
S
F
Chicken
Gallus gallus
P49581
494
57476
Y227
Y
N
C
C
E
E
I
Y
T
D
I
T
Y
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036149
512
57984
I242
F
Y
T
I
N
L
I
I
P
C
L
L
I
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17644
576
65488
Y248
Y
P
C
C
A
E
P
Y
P
D
I
F
F
N
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
F246
Y
P
C
C
E
S
P
F
I
D
I
T
Y
E
I
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
Y272
Y
P
C
C
D
E
I
Y
T
D
I
T
F
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.5
85.8
N.A.
84.6
84.6
N.A.
73.9
79.1
N.A.
69.1
N.A.
40.6
N.A.
46
44.7
Protein Similarity:
100
99.8
97.3
90.2
N.A.
90
90.2
N.A.
79.5
88
N.A.
79.6
N.A.
58.3
N.A.
64.3
61.2
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
100
100
N.A.
20
N.A.
46.6
N.A.
53.3
66.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
N.A.
33.3
N.A.
60
N.A.
60
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
84
84
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
0
0
0
0
84
0
0
0
0
0
% D
% Glu:
0
0
0
0
67
75
0
0
0
0
0
0
0
9
0
% E
% Phe:
9
0
0
0
0
0
0
17
0
0
0
9
17
0
67
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
75
9
9
9
84
0
9
0
17
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
9
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
59
0
0
9
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
25
0
0
0
0
17
0
17
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% R
% Ser:
0
0
0
0
0
9
9
0
0
0
0
0
0
67
0
% S
% Thr:
0
9
9
0
9
0
0
0
67
0
0
75
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
92
9
0
0
0
9
0
75
9
0
0
0
67
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _