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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA6
All Species:
32.42
Human Site:
Y123
Identified Species:
64.85
UniProt:
Q15825
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15825
NP_004189.1
494
56898
Y123
W
K
P
D
I
V
L
Y
N
N
A
V
G
D
F
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
Y123
W
K
P
D
I
V
L
Y
N
N
A
V
G
D
F
Rhesus Macaque
Macaca mulatta
XP_001099152
494
57084
Y123
W
K
P
D
I
V
L
Y
N
N
A
V
G
D
F
Dog
Lupus familis
XP_539951
483
56068
F119
Y
N
N
A
V
G
D
F
Q
V
E
G
K
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0W9
494
56789
Y123
W
K
P
D
I
V
L
Y
N
N
A
V
G
D
F
Rat
Rattus norvegicus
P43143
493
56929
Y123
W
K
P
D
I
V
L
Y
N
N
A
V
G
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509745
552
63776
Y140
W
K
P
D
I
V
L
Y
N
N
A
V
G
D
F
Chicken
Gallus gallus
P49581
494
57476
Y123
W
K
P
D
I
V
L
Y
N
N
A
V
G
D
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036149
512
57984
T138
A
L
L
K
F
D
G
T
I
T
W
V
P
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17644
576
65488
T144
A
D
G
E
Y
V
V
T
T
M
T
K
A
I
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
A142
Y
N
G
T
V
E
W
A
P
P
A
I
Y
K
S
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
Y168
W
T
P
D
L
V
L
Y
N
N
A
D
G
N
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.5
85.8
N.A.
84.6
84.6
N.A.
73.9
79.1
N.A.
69.1
N.A.
40.6
N.A.
46
44.7
Protein Similarity:
100
99.8
97.3
90.2
N.A.
90
90.2
N.A.
79.5
88
N.A.
79.6
N.A.
58.3
N.A.
64.3
61.2
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
6.6
N.A.
6.6
66.6
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
20
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
0
0
9
0
0
75
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
67
0
9
9
0
0
0
0
9
0
59
0
% D
% Glu:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
59
% F
% Gly:
0
0
17
0
0
9
9
0
0
0
0
9
67
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
59
0
0
0
9
0
0
9
0
9
0
% I
% Lys:
0
59
0
9
0
0
0
0
0
0
0
9
9
9
9
% K
% Leu:
0
9
9
0
9
0
67
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
17
9
0
0
0
0
0
67
67
0
0
0
9
0
% N
% Pro:
0
0
67
0
0
0
0
0
9
9
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% S
% Thr:
0
9
0
9
0
0
0
17
9
9
9
0
0
9
0
% T
% Val:
0
0
0
0
17
75
9
0
0
9
0
67
0
0
0
% V
% Trp:
67
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% W
% Tyr:
17
0
0
0
9
0
0
67
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _