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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA6
All Species:
29.39
Human Site:
S445
Identified Species:
58.79
UniProt:
Q15825
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15825
NP_004189.1
494
56898
S445
F
I
A
E
N
M
K
S
H
N
E
T
K
E
V
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
S445
F
I
A
E
N
M
K
S
H
N
E
T
K
E
V
Rhesus Macaque
Macaca mulatta
XP_001099152
494
57084
S445
F
I
A
E
N
M
K
S
H
N
E
T
K
E
V
Dog
Lupus familis
XP_539951
483
56068
N434
F
I
A
E
N
M
K
N
Q
N
E
T
K
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0W9
494
56789
S445
F
I
A
E
N
M
K
S
H
N
E
T
N
E
V
Rat
Rattus norvegicus
P43143
493
56929
S444
F
I
A
E
N
M
K
S
H
N
E
T
K
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509745
552
63776
N462
F
I
A
E
N
M
R
N
Q
N
E
T
K
E
V
Chicken
Gallus gallus
P49581
494
57476
S448
F
I
A
E
N
M
K
S
Q
N
E
T
K
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036149
512
57984
S465
Y
I
A
E
N
M
R
S
R
N
K
A
K
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17644
576
65488
R506
F
I
Q
H
H
M
Q
R
Q
D
E
F
N
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
V457
N
E
E
D
D
K
Q
V
I
E
D
W
K
Y
I
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
S495
F
I
A
Q
H
L
K
S
E
D
E
F
N
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.5
85.8
N.A.
84.6
84.6
N.A.
73.9
79.1
N.A.
69.1
N.A.
40.6
N.A.
46
44.7
Protein Similarity:
100
99.8
97.3
90.2
N.A.
90
90.2
N.A.
79.5
88
N.A.
79.6
N.A.
58.3
N.A.
64.3
61.2
P-Site Identity:
100
100
100
86.6
N.A.
93.3
100
N.A.
80
93.3
N.A.
66.6
N.A.
26.6
N.A.
6.6
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
46.6
N.A.
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
84
0
0
0
0
0
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
0
0
17
9
0
0
0
0
% D
% Glu:
0
9
9
75
0
0
0
0
9
9
84
0
0
75
9
% E
% Phe:
84
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
17
0
0
0
42
0
0
0
0
0
0
% H
% Ile:
0
92
0
0
0
0
0
0
9
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
9
67
0
0
0
9
0
75
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
75
0
0
17
0
75
0
0
25
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
9
0
0
17
0
34
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
17
9
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
84
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _