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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SC4MOL
All Species:
25.76
Human Site:
Y278
Identified Species:
40.48
UniProt:
Q15800
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15800
NP_001017369.1
293
35216
Y278
I
F
G
T
D
S
Q
Y
N
A
Y
N
E
K
R
Chimpanzee
Pan troglodytes
XP_001139385
350
40239
Y335
I
F
G
T
D
S
Q
Y
N
A
Y
N
E
K
R
Rhesus Macaque
Macaca mulatta
XP_001101334
293
35261
Y278
I
F
G
T
D
S
Q
Y
H
A
Y
Y
E
K
R
Dog
Lupus familis
XP_532714
293
35180
F278
I
F
G
T
D
S
Q
F
T
A
Y
N
E
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRA4
293
34754
Y278
L
F
G
T
D
A
Q
Y
H
A
Y
I
E
K
S
Rat
Rattus norvegicus
O35532
293
34945
Y278
I
F
G
T
D
V
Q
Y
H
A
Y
T
E
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507700
296
35185
Y278
L
F
G
T
D
A
Q
Y
L
A
Y
I
E
K
T
Chicken
Gallus gallus
Q5ZLL6
296
35467
F278
I
F
G
T
D
S
Q
F
I
A
Y
K
E
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZW77
291
34789
D275
W
D
R
L
F
D
T
D
S
Q
F
N
K
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20027
300
36047
Y271
L
M
G
Y
H
I
T
Y
A
D
L
K
K
M
T
Sea Urchin
Strong. purpuratus
XP_787442
286
34164
Y269
I
F
G
T
D
M
Q
Y
K
D
Y
Y
A
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105744
264
30720
Y250
L
F
G
T
D
K
D
Y
R
K
A
K
T
I
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39208
281
33124
P266
M
F
G
S
L
R
D
P
L
L
E
E
D
D
N
Baker's Yeast
Sacchar. cerevisiae
P53045
309
36461
P286
C
L
D
T
E
S
G
P
E
A
K
A
S
R
E
Red Bread Mold
Neurospora crassa
Q7SBB6
344
40644
P297
L
G
G
S
Y
R
E
P
D
G
D
M
F
A
K
Conservation
Percent
Protein Identity:
100
64.8
98.6
95.9
N.A.
89
88.7
N.A.
87.1
82
N.A.
78.5
N.A.
N.A.
N.A.
27.3
57.6
Protein Similarity:
100
69.4
99.3
97.9
N.A.
94.8
93.8
N.A.
92.2
90.8
N.A.
89.4
N.A.
N.A.
N.A.
42.6
73
P-Site Identity:
100
100
86.6
80
N.A.
66.6
73.3
N.A.
66.6
73.3
N.A.
6.6
N.A.
N.A.
N.A.
13.3
60
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
80
N.A.
80
80
N.A.
26.6
N.A.
N.A.
N.A.
26.6
60
Percent
Protein Identity:
N.A.
37.2
N.A.
24.2
36.8
20.3
Protein Similarity:
N.A.
54.9
N.A.
41.6
53
37.2
P-Site Identity:
N.A.
33.3
N.A.
13.3
20
6.6
P-Site Similarity:
N.A.
40
N.A.
33.3
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
14
0
0
7
60
7
7
7
7
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
67
7
14
7
7
14
7
0
7
7
0
% D
% Glu:
0
0
0
0
7
0
7
0
7
0
7
7
54
0
20
% E
% Phe:
0
74
0
0
7
0
0
14
0
0
7
0
7
0
0
% F
% Gly:
0
7
87
0
0
0
7
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
20
0
0
0
0
7
0
% H
% Ile:
47
0
0
0
0
7
0
0
7
0
0
14
0
7
0
% I
% Lys:
0
0
0
0
0
7
0
0
7
7
7
20
14
60
7
% K
% Leu:
34
7
0
7
7
0
0
0
14
7
7
0
0
0
7
% L
% Met:
7
7
0
0
0
7
0
0
0
0
0
7
0
7
14
% M
% Asn:
0
0
0
0
0
0
0
0
14
0
0
27
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
60
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
14
0
0
7
0
0
0
0
7
20
% R
% Ser:
0
0
0
14
0
40
0
0
7
0
0
0
7
0
7
% S
% Thr:
0
0
0
74
0
0
14
0
7
0
0
7
7
0
14
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
60
0
0
60
14
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _