Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SC4MOL All Species: 37.58
Human Site: Y244 Identified Species: 59.05
UniProt: Q15800 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15800 NP_001017369.1 293 35216 Y244 P L N L I P F Y A G S R H H D
Chimpanzee Pan troglodytes XP_001139385 350 40239 Y301 P L N L I P F Y A G S R H H D
Rhesus Macaque Macaca mulatta XP_001101334 293 35261 Y244 P L N L I P F Y A G S R H H D
Dog Lupus familis XP_532714 293 35180 Y244 P L N L I P F Y A G S R H H D
Cat Felis silvestris
Mouse Mus musculus Q9CRA4 293 34754 Y244 P L N L V P F Y T G A R H H D
Rat Rattus norvegicus O35532 293 34945 Y244 P L N Y I P F Y T G A R H H D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507700 296 35185 Y244 P L N L I P F Y G G V R H H D
Chicken Gallus gallus Q5ZLL6 296 35467 Y244 P L H L V P F Y A G A R F H D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7ZW77 291 34789 I241 P L N P L H L I P F Y A G A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20027 300 36047 Y237 L H R I F W F Y S G A P A H D
Sea Urchin Strong. purpuratus XP_787442 286 34164 Y235 P L H V I P F Y G G A R F H D
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105744 264 30720 S216 F L P L Y G G S D F H D Y H H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39208 281 33124 V232 I H G N I W P V M G A G Y H T
Baker's Yeast Sacchar. cerevisiae P53045 309 36461 W252 L N K I M P F W A G A E H H D
Red Bread Mold Neurospora crassa Q7SBB6 344 40644 I263 Y Y A N N P V I N G A A C H S
Conservation
Percent
Protein Identity: 100 64.8 98.6 95.9 N.A. 89 88.7 N.A. 87.1 82 N.A. 78.5 N.A. N.A. N.A. 27.3 57.6
Protein Similarity: 100 69.4 99.3 97.9 N.A. 94.8 93.8 N.A. 92.2 90.8 N.A. 89.4 N.A. N.A. N.A. 42.6 73
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 86.6 73.3 N.A. 20 N.A. N.A. N.A. 33.3 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. 86.6 93.3 N.A. 26.6 N.A. N.A. N.A. 53.3 86.6
Percent
Protein Identity: N.A. 37.2 N.A. 24.2 36.8 20.3
Protein Similarity: N.A. 54.9 N.A. 41.6 53 37.2
P-Site Identity: N.A. 20 N.A. 20 46.6 20
P-Site Similarity: N.A. 26.6 N.A. 33.3 73.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 40 0 54 14 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 74 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 7 0 0 0 7 0 74 0 0 14 0 0 14 0 0 % F
% Gly: 0 0 7 0 0 7 7 0 14 87 0 7 7 0 0 % G
% His: 0 14 14 0 0 7 0 0 0 0 7 0 54 94 7 % H
% Ile: 7 0 0 14 54 0 0 14 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 14 74 0 54 7 0 7 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 7 54 14 7 0 0 0 7 0 0 0 0 0 0 % N
% Pro: 67 0 7 7 0 74 7 0 7 0 0 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 0 0 0 0 0 0 0 60 0 0 7 % R
% Ser: 0 0 0 0 0 0 0 7 7 0 27 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 7 % T
% Val: 0 0 0 7 14 0 7 7 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 14 0 7 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 7 7 0 0 67 0 0 7 0 14 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _