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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAB1 All Species: 9.09
Human Site: S373 Identified Species: 25
UniProt: Q15750 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15750 NP_006107.1 504 54644 S373 G Y P L G E M S Q P T P S P A
Chimpanzee Pan troglodytes XP_515141 760 82338 S629 G Y P L G E M S Q P T P S P A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849785 504 54531 S373 G Y P L G E M S Q P T P S P A
Cat Felis silvestris
Mouse Mus musculus Q8CF89 502 54598 E371 N F G Y P L G E M S Q P T P T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519792 390 41520 L260 T R K P G P F L P R E D P P P
Chicken Gallus gallus NP_001006240 438 47684 E308 G P G Q A N Q E I A A M I A T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002662286 386 41817 L256 Y T L A D G S L T P T Q G G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395188 475 53714 V345 A Q A V V D K V V R I H H D I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783278 730 82115 M551 N F P L G N R M S S P A P A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.3 N.A. 98 N.A. 97.2 N.A. N.A. 35.3 77.9 N.A. 49.4 N.A. N.A. 40.6 N.A. 28.7
Protein Similarity: 100 66.3 N.A. 99.2 N.A. 99 N.A. N.A. 46 82.3 N.A. 59.9 N.A. N.A. 58.7 N.A. 44.3
P-Site Identity: 100 100 N.A. 100 N.A. 13.3 N.A. N.A. 13.3 6.6 N.A. 13.3 N.A. N.A. 0 N.A. 26.6
P-Site Similarity: 100 100 N.A. 100 N.A. 26.6 N.A. N.A. 13.3 6.6 N.A. 13.3 N.A. N.A. 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 12 12 0 0 0 0 12 12 12 0 23 45 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 12 0 0 0 0 0 12 0 12 0 % D
% Glu: 0 0 0 0 0 34 0 23 0 0 12 0 0 0 0 % E
% Phe: 0 23 0 0 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 45 0 23 0 56 12 12 0 0 0 0 0 12 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 0 12 0 12 0 12 % I
% Lys: 0 0 12 0 0 0 12 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 12 45 0 12 0 23 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 34 12 12 0 0 12 0 0 0 % M
% Asn: 23 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 45 12 12 12 0 0 12 45 12 45 23 56 12 % P
% Gln: 0 12 0 12 0 0 12 0 34 0 12 12 0 0 0 % Q
% Arg: 0 12 0 0 0 0 12 0 0 23 0 0 0 0 12 % R
% Ser: 0 0 0 0 0 0 12 34 12 23 0 0 34 0 0 % S
% Thr: 12 12 0 0 0 0 0 0 12 0 45 0 12 0 23 % T
% Val: 0 0 0 12 12 0 0 12 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 34 0 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _