KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZRSR2
All Species:
4.85
Human Site:
S422
Identified Species:
11.85
UniProt:
Q15696
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15696
NP_005080.1
482
58045
S422
R
E
R
H
N
S
R
S
R
G
R
N
R
D
R
Chimpanzee
Pan troglodytes
XP_520951
539
64009
H479
T
S
K
S
R
E
R
H
N
S
R
S
R
G
R
Rhesus Macaque
Macaca mulatta
XP_001116975
508
60654
S448
K
S
R
E
R
H
N
S
R
S
R
G
R
N
K
Dog
Lupus familis
XP_548872
455
54370
R396
K
R
N
G
E
A
E
R
K
R
R
S
S
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64707
428
51346
E356
G
K
N
S
D
R
R
E
R
K
D
H
H
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515642
557
65450
K497
R
S
S
H
R
S
S
K
Y
H
K
S
S
S
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392139
453
54523
E394
E
S
P
E
P
E
I
E
H
R
S
K
T
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788119
684
80883
R417
S
S
R
R
F
S
Q
R
R
S
R
S
R
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148499
305
35315
G246
D
D
G
A
G
R
G
G
R
H
D
R
Y
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SY74
757
89047
S688
S
D
K
D
R
D
R
S
K
Q
R
Q
R
Y
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
93.5
84.4
N.A.
68.2
N.A.
N.A.
67.8
N.A.
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
33.6
Protein Similarity:
100
88.3
93.9
88.5
N.A.
77.8
N.A.
N.A.
76.3
N.A.
N.A.
N.A.
N.A.
N.A.
56
N.A.
48.2
P-Site Identity:
100
26.6
33.3
13.3
N.A.
13.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
40
P-Site Similarity:
100
40
53.3
40
N.A.
40
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
60
Percent
Protein Identity:
N.A.
21.9
N.A.
29.3
N.A.
N.A.
Protein Similarity:
N.A.
33.8
N.A.
41.8
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
20
0
10
10
10
0
0
0
0
20
0
0
20
10
% D
% Glu:
10
10
0
20
10
20
10
20
0
0
0
0
0
20
20
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
10
10
0
10
10
0
10
0
10
0
10
0
% G
% His:
0
0
0
20
0
10
0
10
10
20
0
10
10
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
20
10
20
0
0
0
0
10
20
10
10
10
0
0
20
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
20
0
10
0
10
0
10
0
0
10
0
10
0
% N
% Pro:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% Q
% Arg:
20
10
30
10
40
20
40
20
50
20
60
10
50
0
50
% R
% Ser:
20
50
10
20
0
30
10
30
0
30
10
40
20
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _