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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RHOH All Species: 22.12
Human Site: S184 Identified Species: 34.76
UniProt: Q15669 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15669 NP_004301.1 191 21331 S184 R N R R R L F S I N E C K I F
Chimpanzee Pan troglodytes XP_001143212 191 21282 S184 R N R R R L F S I N E C K I F
Rhesus Macaque Macaca mulatta XP_001094054 191 21326 S184 R N R R R L F S I N E C K I F
Dog Lupus familis XP_545951 191 21338 S184 R N R R R F F S I N E C K I F
Cat Felis silvestris
Mouse Mus musculus Q9D3G9 191 21306 S184 R N R R K L F S I N E C K I F
Rat Rattus norvegicus Q6RUV5 192 21432 V182 A V L C P P P V K K R K R K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505562 191 21105 S184 Q R R R K L F S I N E C R I F
Chicken Gallus gallus Q90694 191 21254 P182 A A L E P P E P K K T R R C V
Frog Xenopus laevis NP_001079368 191 21285 P182 A A L E P P E P K K K R K C M
Zebra Danio Brachydanio rerio XP_002660498 195 21854 N188 Q T R R R L L N L N P C K I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40793 191 21384 P182 A A L E P P E P T K K R K C K
Honey Bee Apis mellifera XP_624520 195 21847 Q185 A V L R P E P Q K R R Q R R C
Nematode Worm Caenorhab. elegans Q03206 191 21436 R182 A V L T P P Q R A K K S K C T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XGU0 209 22953
Baker's Yeast Sacchar. cerevisiae P19073 191 21304 I182 A A L E P P V I K K S K K C A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.4 96.8 N.A. 96.8 40 N.A. 87.9 42.9 42.4 74.8 N.A. 43.9 43 42.4 N.A.
Protein Similarity: 100 99.4 100 98.9 N.A. 99.4 63.5 N.A. 96.3 63.3 63.8 87.1 N.A. 64.4 63.5 65.4 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 0 N.A. 73.3 0 6.6 53.3 N.A. 6.6 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 6.6 N.A. 93.3 6.6 13.3 73.3 N.A. 13.3 13.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36.8 40.8 N.A.
Protein Similarity: N.A. N.A. N.A. 60.2 62.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 27 0 0 0 0 0 0 7 0 0 0 0 0 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 47 0 34 14 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 27 0 7 20 0 0 0 40 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 40 0 0 0 0 0 0 0 40 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 40 0 0 0 0 47 0 % I
% Lys: 0 0 0 0 14 0 0 0 34 40 20 14 67 7 7 % K
% Leu: 0 0 47 0 0 40 7 0 7 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 34 0 0 0 0 0 7 0 47 0 0 0 0 0 % N
% Pro: 0 0 0 0 47 40 14 20 0 0 7 0 0 0 0 % P
% Gln: 14 0 0 0 0 0 7 7 0 0 0 7 0 0 0 % Q
% Arg: 34 7 47 54 34 0 0 7 0 7 14 20 27 7 0 % R
% Ser: 0 0 0 0 0 0 0 40 0 0 7 7 0 0 7 % S
% Thr: 0 7 0 7 0 0 0 0 7 0 7 0 0 0 7 % T
% Val: 0 20 0 0 0 0 7 7 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _