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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP4
All Species:
35.15
Human Site:
S458
Identified Species:
64.44
UniProt:
Q15650
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15650
NP_057297.2
581
66146
S458
I
K
R
V
E
G
R
S
W
Y
T
P
H
R
G
Chimpanzee
Pan troglodytes
XP_510472
581
66144
S458
I
K
R
V
E
G
R
S
W
Y
T
P
H
R
G
Rhesus Macaque
Macaca mulatta
XP_001107836
581
66108
S458
I
K
R
V
E
G
R
S
W
Y
T
P
H
R
G
Dog
Lupus familis
XP_535513
581
66444
N458
I
K
R
V
E
G
R
N
W
Y
T
P
H
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXN3
581
66189
S458
I
K
R
V
E
G
R
S
W
Y
T
P
H
R
G
Rat
Rattus norvegicus
NP_001128453
581
65833
S458
I
K
R
V
E
G
R
S
W
Y
T
P
H
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509179
577
65839
T454
I
K
R
V
E
G
R
T
W
Y
T
S
H
R
G
Chicken
Gallus gallus
XP_413717
620
69438
T497
I
K
R
V
E
G
R
T
W
Y
T
S
H
R
G
Frog
Xenopus laevis
NP_001085378
567
64726
T448
I
K
Q
V
E
G
R
T
W
Y
S
A
H
R
G
Zebra Danio
Brachydanio rerio
NP_001071043
564
64113
T444
I
K
R
V
E
G
R
T
W
Y
T
S
H
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608393
513
57746
I413
K
E
P
H
A
E
D
I
A
Q
M
E
G
F
Y
Honey Bee
Apis mellifera
XP_624783
476
55388
E377
R
E
E
I
S
N
V
E
Q
Y
Y
R
V
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787043
567
63930
H452
G
R
T
W
Y
S
P
H
R
G
R
L
W
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.9
90.5
N.A.
88.8
88.6
N.A.
77.2
65.6
61
58
N.A.
32.8
37.6
N.A.
43.8
Protein Similarity:
100
100
99.1
95.5
N.A.
93.6
93.2
N.A.
86.9
77.9
76.2
76
N.A.
54.9
56.9
N.A.
62.6
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
86.6
73.3
86.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
6.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
16
8
0
77
8
0
8
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
77
0
0
0
8
0
0
8
0
77
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
77
0
0
% H
% Ile:
77
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
8
77
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
8
0
0
0
0
47
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
8
8
70
0
0
0
77
0
8
0
8
8
0
77
0
% R
% Ser:
0
0
0
0
8
8
0
39
0
0
8
24
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
31
0
0
70
0
0
0
0
% T
% Val:
0
0
0
77
0
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
77
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
85
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _