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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGN
All Species:
29.39
Human Site:
Y259
Identified Species:
58.79
UniProt:
Q15493
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15493
NP_004674.1
299
33253
Y259
G
K
N
Y
S
E
M
Y
V
T
C
A
R
D
G
Chimpanzee
Pan troglodytes
XP_001141501
148
16139
I118
G
R
Y
F
A
G
K
I
S
L
N
T
Y
L
L
Rhesus Macaque
Macaca mulatta
XP_001090600
299
33203
Y259
G
K
N
Y
S
E
M
Y
V
T
C
A
R
D
G
Dog
Lupus familis
XP_538011
343
37764
Y303
G
K
D
Y
S
E
M
Y
V
T
C
A
R
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q64374
299
33388
Y259
G
K
D
Y
S
E
M
Y
V
T
C
A
R
D
G
Rat
Rattus norvegicus
Q03336
299
33371
Y259
G
K
D
Y
S
E
M
Y
V
T
C
A
R
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505641
270
28328
G240
S
A
R
E
G
M
D
G
A
W
L
S
K
Q
P
Chicken
Gallus gallus
Q9I923
299
33211
Y259
G
K
D
Y
S
E
M
Y
V
T
S
A
S
D
G
Frog
Xenopus laevis
Q9I922
299
33069
Y259
G
P
D
Y
S
E
M
Y
V
T
S
A
C
D
G
Zebra Danio
Brachydanio rerio
Q6TLF6
295
32791
Y255
G
K
D
Y
S
D
L
Y
I
T
S
A
Y
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397069
313
34194
L268
G
G
P
N
L
D
I
L
Y
V
T
S
A
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780550
245
27043
E215
A
K
H
F
L
T
E
E
Q
K
R
T
Q
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.1
98.3
79.5
N.A.
88.6
88.6
N.A.
57.8
77.9
70.2
63.2
N.A.
N.A.
41.5
N.A.
40.1
Protein Similarity:
100
47.8
99.3
82.8
N.A.
93.6
93.3
N.A.
70.5
85.9
84.6
78.9
N.A.
N.A.
56.2
N.A.
54.1
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
0
80
73.3
53.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
13.3
86.6
80
80
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
0
0
9
0
0
67
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
42
0
9
0
0
% C
% Asp:
0
0
50
0
0
17
9
0
0
0
0
0
0
59
0
% D
% Glu:
0
0
0
9
0
59
9
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
84
9
0
0
9
9
0
9
0
0
0
0
0
0
67
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
9
0
0
0
0
9
0
% I
% Lys:
0
67
0
0
0
0
9
0
0
9
0
0
9
0
0
% K
% Leu:
0
0
0
0
17
0
9
9
0
9
9
0
0
9
17
% L
% Met:
0
0
0
0
0
9
59
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
9
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
9
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
9
9
0
% Q
% Arg:
0
9
9
0
0
0
0
0
0
0
9
0
42
9
0
% R
% Ser:
9
0
0
0
67
0
0
0
9
0
25
17
9
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
67
9
17
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
59
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
9
67
0
0
0
67
9
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _