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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGN
All Species:
29.39
Human Site:
S188
Identified Species:
58.79
UniProt:
Q15493
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15493
NP_004674.1
299
33253
S188
D
L
Q
T
G
Q
I
S
N
R
R
S
V
Y
K
Chimpanzee
Pan troglodytes
XP_001141501
148
16139
A56
V
Q
R
V
T
M
D
A
P
V
S
S
V
A
L
Rhesus Macaque
Macaca mulatta
XP_001090600
299
33203
S188
D
L
Q
T
G
Q
I
S
N
R
R
S
V
Y
K
Dog
Lupus familis
XP_538011
343
37764
S232
D
L
Q
T
G
K
I
S
N
R
R
S
V
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64374
299
33388
S188
D
L
Q
T
G
Q
I
S
N
R
R
I
V
Y
K
Rat
Rattus norvegicus
Q03336
299
33371
S188
D
L
P
T
G
Q
I
S
N
R
R
T
V
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505641
270
28328
I179
G
I
P
D
G
M
C
I
D
A
D
G
K
L
W
Chicken
Gallus gallus
Q9I923
299
33211
G188
D
L
Q
T
G
K
I
G
N
R
R
S
V
Y
K
Frog
Xenopus laevis
Q9I922
299
33069
S188
D
M
K
T
G
K
S
S
N
R
R
T
L
Y
K
Zebra Danio
Brachydanio rerio
Q6TLF6
295
32791
S184
D
I
Q
T
G
G
L
S
N
R
R
T
V
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397069
313
34194
S195
N
S
Q
T
G
I
I
S
N
K
K
I
V
F
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780550
245
27043
D154
L
P
D
G
M
C
I
D
S
E
G
M
L
W
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.1
98.3
79.5
N.A.
88.6
88.6
N.A.
57.8
77.9
70.2
63.2
N.A.
N.A.
41.5
N.A.
40.1
Protein Similarity:
100
47.8
99.3
82.8
N.A.
93.6
93.3
N.A.
70.5
85.9
84.6
78.9
N.A.
N.A.
56.2
N.A.
54.1
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
86.6
N.A.
6.6
86.6
60
73.3
N.A.
N.A.
46.6
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
20
93.3
93.3
93.3
N.A.
N.A.
73.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
9
9
0
0
9
9
9
0
9
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
9
84
9
0
9
0
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
9
67
9
0
0
0
17
0
0
0
% I
% Lys:
0
0
9
0
0
25
0
0
0
9
9
0
9
0
67
% K
% Leu:
9
50
0
0
0
0
9
0
0
0
0
0
17
9
9
% L
% Met:
0
9
0
0
9
17
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% N
% Pro:
0
9
17
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
9
59
0
0
34
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
67
67
0
0
0
0
% R
% Ser:
0
9
0
0
0
0
9
67
9
0
9
42
0
0
0
% S
% Thr:
0
0
0
75
9
0
0
0
0
0
0
25
0
0
0
% T
% Val:
9
0
0
9
0
0
0
0
0
9
0
0
75
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _