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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGN
All Species:
30.3
Human Site:
S172
Identified Species:
60.61
UniProt:
Q15493
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15493
NP_004674.1
299
33253
S172
F
Y
Y
I
D
S
L
S
Y
S
V
D
A
F
D
Chimpanzee
Pan troglodytes
XP_001141501
148
16139
C40
D
I
P
A
K
K
V
C
R
W
D
S
F
T
K
Rhesus Macaque
Macaca mulatta
XP_001090600
299
33203
S172
F
Y
Y
I
D
S
L
S
Y
S
V
D
A
F
D
Dog
Lupus familis
XP_538011
343
37764
S216
F
Y
Y
I
D
S
L
S
Y
S
V
D
A
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q64374
299
33388
S172
F
Y
Y
I
D
S
L
S
Y
T
V
D
A
F
D
Rat
Rattus norvegicus
Q03336
299
33371
S172
F
Y
Y
I
D
S
L
S
Y
T
V
D
A
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505641
270
28328
A163
G
P
G
A
E
R
R
A
V
Y
R
L
E
E
E
Chicken
Gallus gallus
Q9I923
299
33211
S172
F
F
Y
I
D
S
L
S
Y
S
V
D
A
F
D
Frog
Xenopus laevis
Q9I922
299
33069
S172
L
Y
Y
I
D
S
L
S
F
K
V
D
A
L
D
Zebra Danio
Brachydanio rerio
Q6TLF6
295
32791
A168
F
Y
Y
I
D
S
L
A
F
M
V
E
A
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397069
313
34194
S179
F
Y
Y
I
D
S
L
S
Y
Q
I
V
A
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780550
245
27043
V138
E
L
A
N
R
R
Q
V
V
K
V
P
D
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.1
98.3
79.5
N.A.
88.6
88.6
N.A.
57.8
77.9
70.2
63.2
N.A.
N.A.
41.5
N.A.
40.1
Protein Similarity:
100
47.8
99.3
82.8
N.A.
93.6
93.3
N.A.
70.5
85.9
84.6
78.9
N.A.
N.A.
56.2
N.A.
54.1
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
0
93.3
73.3
73.3
N.A.
N.A.
66.6
N.A.
6.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
20
100
80
93.3
N.A.
N.A.
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
0
0
0
17
0
0
0
0
75
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
75
0
0
0
0
0
9
59
9
0
67
% D
% Glu:
9
0
0
0
9
0
0
0
0
0
0
9
9
17
17
% E
% Phe:
67
9
0
0
0
0
0
0
17
0
0
0
9
59
0
% F
% Gly:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
75
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
9
9
0
0
0
17
0
0
0
0
9
% K
% Leu:
9
9
0
0
0
0
75
0
0
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
9
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
17
9
0
9
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
0
75
0
67
0
34
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
17
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
9
9
17
0
75
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
67
75
0
0
0
0
0
59
9
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _