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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKIV2L
All Species:
20.91
Human Site:
T185
Identified Species:
41.82
UniProt:
Q15477
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15477
NP_008860.4
1246
137799
T185
D
F
E
K
D
L
L
T
I
P
P
G
F
K
K
Chimpanzee
Pan troglodytes
XP_001160927
1246
137607
T185
D
F
E
K
D
L
L
T
I
P
P
G
F
K
K
Rhesus Macaque
Macaca mulatta
XP_001106475
1196
132165
D178
E
E
A
E
E
E
I
D
F
E
K
D
L
L
T
Dog
Lupus familis
XP_538841
1246
137947
T185
D
F
E
Q
D
L
L
T
V
P
P
G
F
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU3
1040
117618
D92
N
E
D
L
S
L
A
D
L
M
P
R
V
K
V
Rat
Rattus norvegicus
NP_998724
1241
136937
T185
D
F
E
K
D
L
L
T
V
P
P
G
F
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038366
1230
137394
T192
D
F
E
K
D
L
M
T
V
P
P
G
L
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524465
1197
135749
Q169
D
L
L
E
N
L
E
Q
D
L
D
V
Q
E
W
Honey Bee
Apis mellifera
XP_397131
1212
138972
T175
N
Y
T
P
K
E
K
T
I
Q
E
Q
E
S
L
Nematode Worm
Caenorhab. elegans
Q23223
1026
116352
A78
E
E
E
E
V
E
E
A
R
M
E
N
I
I
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190280
1347
151165
T203
L
N
G
G
P
A
Q
T
V
P
P
S
F
K
Q
Baker's Yeast
Sacchar. cerevisiae
P35207
1287
146040
D195
K
D
G
Q
G
L
F
D
I
P
E
G
M
N
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
92.6
94.5
N.A.
32.7
93.2
N.A.
N.A.
N.A.
N.A.
60.2
N.A.
42.6
40.8
32.1
N.A.
Protein Similarity:
100
99.6
93.6
96.8
N.A.
48.6
96.5
N.A.
N.A.
N.A.
N.A.
74.3
N.A.
58.3
59.5
49.1
N.A.
P-Site Identity:
100
100
0
86.6
N.A.
20
93.3
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
40
100
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
33.3
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.1
37.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
54
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
9
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
9
9
0
42
0
0
25
9
0
9
9
0
0
0
% D
% Glu:
17
25
50
25
9
25
17
0
0
9
25
0
9
9
0
% E
% Phe:
0
42
0
0
0
0
9
0
9
0
0
0
42
0
0
% F
% Gly:
0
0
17
9
9
0
0
0
0
0
0
50
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
34
0
0
0
9
9
0
% I
% Lys:
9
0
0
34
9
0
9
0
0
0
9
0
0
59
34
% K
% Leu:
9
9
9
9
0
67
34
0
9
9
0
0
17
9
9
% L
% Met:
0
0
0
0
0
0
9
0
0
17
0
0
9
0
0
% M
% Asn:
17
9
0
0
9
0
0
0
0
0
0
9
0
9
0
% N
% Pro:
0
0
0
9
9
0
0
0
0
59
59
0
0
0
0
% P
% Gln:
0
0
0
17
0
0
9
9
0
9
0
9
9
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
9
% R
% Ser:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% S
% Thr:
0
0
9
0
0
0
0
59
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
9
0
0
0
34
0
0
9
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _