KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKIV2L
All Species:
14.24
Human Site:
S248
Identified Species:
28.48
UniProt:
Q15477
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15477
NP_008860.4
1246
137799
S248
T
V
S
A
S
P
C
S
A
P
L
A
R
A
S
Chimpanzee
Pan troglodytes
XP_001160927
1246
137607
S248
A
V
S
A
S
P
C
S
A
P
L
A
R
A
S
Rhesus Macaque
Macaca mulatta
XP_001106475
1196
132165
D224
P
L
D
L
G
G
G
D
E
D
E
N
E
A
V
Dog
Lupus familis
XP_538841
1246
137947
S248
T
V
S
A
T
P
C
S
A
S
L
A
R
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU3
1040
117618
L138
A
K
E
Y
P
F
I
L
D
A
F
Q
R
E
A
Rat
Rattus norvegicus
NP_998724
1241
136937
S242
A
A
S
A
S
P
S
S
T
P
L
I
R
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038366
1230
137394
L256
R
T
N
S
L
E
D
L
G
I
K
D
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524465
1197
135749
K215
D
V
D
D
H
I
M
K
A
D
L
K
P
V
L
Honey Bee
Apis mellifera
XP_397131
1212
138972
E226
D
E
I
T
S
L
L
E
E
R
D
I
P
I
L
Nematode Worm
Caenorhab. elegans
Q23223
1026
116352
F124
E
P
A
K
Y
Y
P
F
Q
L
D
A
F
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190280
1347
151165
S293
A
S
I
S
N
E
V
S
K
G
L
E
T
D
V
Baker's Yeast
Sacchar. cerevisiae
P35207
1287
146040
T267
E
E
A
T
E
E
T
T
A
D
N
A
D
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
92.6
94.5
N.A.
32.7
93.2
N.A.
N.A.
N.A.
N.A.
60.2
N.A.
42.6
40.8
32.1
N.A.
Protein Similarity:
100
99.6
93.6
96.8
N.A.
48.6
96.5
N.A.
N.A.
N.A.
N.A.
74.3
N.A.
58.3
59.5
49.1
N.A.
P-Site Identity:
100
93.3
6.6
86.6
N.A.
6.6
66.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
20
6.6
6.6
N.A.
P-Site Similarity:
100
93.3
13.3
93.3
N.A.
13.3
66.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
20
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.1
37.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
54
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
17
34
0
0
0
0
42
9
0
42
0
42
17
% A
% Cys:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
17
9
0
0
9
9
9
25
17
9
9
17
0
% D
% Glu:
17
17
9
0
9
25
0
9
17
0
9
9
9
9
0
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
9
0
9
0
0
% F
% Gly:
0
0
0
0
9
9
9
0
9
9
0
0
0
9
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
9
9
0
0
9
0
17
0
9
0
% I
% Lys:
0
9
0
9
0
0
0
9
9
0
9
9
0
0
9
% K
% Leu:
0
9
0
9
9
9
9
17
0
9
50
0
0
0
17
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
0
9
9
0
0
0
% N
% Pro:
9
9
0
0
9
34
9
0
0
25
0
0
17
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
9
0
9
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
9
0
0
42
0
0
% R
% Ser:
0
9
34
17
34
0
9
42
0
9
0
0
9
0
42
% S
% Thr:
17
9
0
17
9
0
9
9
9
0
0
0
9
0
0
% T
% Val:
0
34
0
0
0
0
9
0
0
0
0
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _