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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC23A
All Species:
39.39
Human Site:
T498
Identified Species:
72.22
UniProt:
Q15436
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15436
NP_006355.2
765
86161
T498
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
D
Chimpanzee
Pan troglodytes
XP_509915
748
84571
G490
T
Q
Y
Q
H
S
S
G
Q
R
R
I
R
V
T
Rhesus Macaque
Macaca mulatta
XP_001091771
765
86128
T498
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
D
Dog
Lupus familis
XP_850832
765
86260
T498
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q01405
765
86143
T498
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513018
765
86087
T498
Q
R
R
I
R
V
T
T
V
A
R
N
W
A
D
Chicken
Gallus gallus
Q5ZK03
767
86285
T500
Q
K
R
I
R
V
T
T
I
A
R
N
W
A
D
Frog
Xenopus laevis
NP_001086405
741
83183
L484
G
R
G
A
V
Q
F
L
T
Q
Y
Q
H
S
S
Zebra Danio
Brachydanio rerio
Q7SZE5
765
86062
T498
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392515
768
85881
T501
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780042
764
86244
T499
Q
R
R
V
R
V
T
T
L
A
R
N
W
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15303
768
85366
V504
S
G
T
N
R
I
R
V
T
T
V
A
N
Q
L
Red Bread Mold
Neurospora crassa
Q9C284
775
86260
T504
H
F
H
L
R
V
T
T
I
A
R
N
L
S
G
Conservation
Percent
Protein Identity:
100
96.8
99.8
97.9
N.A.
98.9
N.A.
N.A.
97.5
85.5
82.6
90.9
N.A.
N.A.
75
N.A.
78
Protein Similarity:
100
97.2
100
98.8
N.A.
99.8
N.A.
N.A.
99.4
93
89.5
95.4
N.A.
N.A.
86.9
N.A.
88.2
P-Site Identity:
100
6.6
100
100
N.A.
100
N.A.
N.A.
93.3
93.3
6.6
100
N.A.
N.A.
100
N.A.
86.6
P-Site Similarity:
100
20
100
100
N.A.
100
N.A.
N.A.
100
100
13.3
100
N.A.
N.A.
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.9
56.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
68.2
71.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
77
0
8
0
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
0
8
0
0
0
0
0
0
8
% G
% His:
8
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
62
0
8
0
0
62
0
0
8
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
8
8
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
77
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
70
8
0
8
0
8
0
0
8
8
0
8
0
8
0
% Q
% Arg:
0
70
70
0
85
0
8
0
0
8
85
0
8
0
0
% R
% Ser:
8
0
0
0
0
8
8
0
0
0
0
0
0
16
8
% S
% Thr:
8
0
8
0
0
0
77
77
16
8
0
0
0
0
8
% T
% Val:
0
0
0
8
8
77
0
8
8
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _