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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC23A All Species: 22.42
Human Site: T212 Identified Species: 41.11
UniProt: Q15436 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15436 NP_006355.2 765 86161 T212 G L S K V P L T Q A T R G P Q
Chimpanzee Pan troglodytes XP_509915 748 84571 T212 G L S K V P V T Q A T R G P Q
Rhesus Macaque Macaca mulatta XP_001091771 765 86128 T212 G L S K V P V T Q A T R G P Q
Dog Lupus familis XP_850832 765 86260 T212 G L S K V P V T Q A T R G P Q
Cat Felis silvestris
Mouse Mus musculus Q01405 765 86143 T212 G L S K V P V T Q A T R G P Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513018 765 86087 T212 G L S K V P V T Q A A R G P Q
Chicken Gallus gallus Q5ZK03 767 86285 P212 G L S R P A V P I Q Q G R P L
Frog Xenopus laevis NP_001086405 741 83183 P212 G L S K A A A P A Q Q G R P I
Zebra Danio Brachydanio rerio Q7SZE5 765 86062 A212 G L T K P A A A Q A G R G P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392515 768 85881 G212 G I G R P I P G Q N P N Q Q R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780042 764 86244 Q211 G I G R V P A Q A Q R G N Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P15303 768 85366 N214 G A A S H L P N A M N K V T P
Red Bread Mold Neurospora crassa Q9C284 775 86260 R213 G L V Q P A M R P G M P M Q Q
Conservation
Percent
Protein Identity: 100 96.8 99.8 97.9 N.A. 98.9 N.A. N.A. 97.5 85.5 82.6 90.9 N.A. N.A. 75 N.A. 78
Protein Similarity: 100 97.2 100 98.8 N.A. 99.8 N.A. N.A. 99.4 93 89.5 95.4 N.A. N.A. 86.9 N.A. 88.2
P-Site Identity: 100 93.3 93.3 93.3 N.A. 93.3 N.A. N.A. 86.6 26.6 33.3 60 N.A. N.A. 13.3 N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 40 33.3 66.6 N.A. N.A. 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50.9 56.7
Protein Similarity: N.A. N.A. N.A. N.A. 68.2 71.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 31 24 8 24 54 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 100 0 16 0 0 0 0 8 0 8 8 24 54 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 0 0 0 8 0 0 8 0 0 0 0 0 8 % I
% Lys: 0 0 0 62 0 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 77 0 0 0 8 8 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 8 8 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 8 8 8 0 0 % N
% Pro: 0 0 0 0 31 54 16 16 8 0 8 8 0 70 8 % P
% Gln: 0 0 0 8 0 0 0 8 62 24 16 0 8 24 70 % Q
% Arg: 0 0 0 24 0 0 0 8 0 0 8 54 16 0 8 % R
% Ser: 0 0 62 8 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 0 0 0 47 0 0 39 0 0 8 0 % T
% Val: 0 0 8 0 54 0 47 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _