KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3C
All Species:
23.03
Human Site:
Y731
Identified Species:
36.19
UniProt:
Q15386
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15386
NP_055486.2
1083
123923
Y731
N
V
T
I
R
R
N
Y
I
Y
E
D
A
Y
D
Chimpanzee
Pan troglodytes
XP_528010
1089
124652
Y737
N
V
T
I
R
R
N
Y
I
Y
E
D
A
Y
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539937
1088
124202
Y736
N
V
T
I
R
R
N
Y
I
Y
E
D
A
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80U95
1083
123957
Y731
N
V
T
I
R
R
N
Y
I
Y
E
D
A
Y
D
Rat
Rattus norvegicus
Q62940
887
102376
S583
R
E
W
F
F
L
I
S
K
E
M
F
N
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510756
1084
124281
Y732
N
V
T
I
R
R
N
Y
I
Y
E
D
A
Y
D
Chicken
Gallus gallus
NP_001026138
1084
124128
Y732
N
V
T
I
R
R
N
Y
I
Y
E
D
A
Y
D
Frog
Xenopus laevis
Q6DCL5
944
106566
S640
R
E
W
F
D
I
L
S
S
E
M
I
N
P
D
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
L461
V
A
R
E
W
L
Y
L
L
S
H
E
M
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611896
1122
128925
H772
L
I
T
V
R
R
S
H
L
Y
E
D
A
Y
D
Honey Bee
Apis mellifera
XP_396547
1033
119022
Q707
L
R
L
K
M
R
V
Q
L
F
N
T
A
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797123
1037
118587
V713
D
L
R
K
K
L
R
V
T
L
K
N
A
Q
G
Poplar Tree
Populus trichocarpa
XP_002314972
1027
117409
F698
R
G
L
I
R
V
S
F
I
N
E
F
G
V
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
F700
R
S
S
I
R
V
T
F
V
N
E
L
G
V
E
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
L606
G
G
I
T
K
E
F
L
T
T
V
S
D
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
N.A.
95.4
N.A.
93.3
22.1
N.A.
91.4
90.6
22.8
22.5
N.A.
39.7
43
N.A.
44.2
Protein Similarity:
100
98.1
N.A.
97.4
N.A.
97.2
38.4
N.A.
95.6
94.8
39
38.3
N.A.
61
62.7
N.A.
61.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
100
100
6.6
0
N.A.
60
13.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
0
N.A.
100
100
6.6
20
N.A.
93.3
26.6
N.A.
40
Percent
Protein Identity:
28.3
N.A.
N.A.
28.7
26.7
N.A.
Protein Similarity:
47
N.A.
N.A.
49
44.9
N.A.
P-Site Identity:
26.6
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
46.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
0
0
60
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
0
0
0
0
0
47
7
0
54
% D
% Glu:
0
14
0
7
0
7
0
0
0
14
60
7
0
7
14
% E
% Phe:
0
0
0
14
7
0
7
14
0
7
0
14
0
0
0
% F
% Gly:
7
14
0
0
0
0
0
0
0
0
0
0
14
7
14
% G
% His:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% H
% Ile:
0
7
7
54
0
7
7
0
47
0
0
7
0
0
0
% I
% Lys:
0
0
0
14
14
0
0
0
7
0
7
0
0
0
0
% K
% Leu:
14
7
14
0
0
20
7
14
20
7
0
7
0
7
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
14
0
7
0
0
% M
% Asn:
40
0
0
0
0
0
40
0
0
14
7
7
14
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% Q
% Arg:
27
7
14
0
60
54
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
7
0
0
0
14
14
7
7
0
7
0
0
0
% S
% Thr:
0
0
47
7
0
0
7
0
14
7
0
7
0
0
0
% T
% Val:
7
40
0
7
0
14
7
7
7
0
7
0
0
14
0
% V
% Trp:
0
0
14
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
40
0
47
0
0
0
47
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _