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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3C
All Species:
23.64
Human Site:
S251
Identified Species:
37.14
UniProt:
Q15386
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15386
NP_055486.2
1083
123923
S251
P
L
H
F
T
Y
N
S
C
P
E
G
A
R
Q
Chimpanzee
Pan troglodytes
XP_528010
1089
124652
S257
P
L
H
F
T
Y
N
S
C
P
E
G
A
R
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539937
1088
124202
S251
P
L
H
F
T
Y
N
S
C
P
E
G
A
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80U95
1083
123957
S251
P
L
H
F
T
Y
S
S
C
P
E
A
S
R
H
Rat
Rattus norvegicus
Q62940
887
102376
K127
I
K
K
S
L
N
P
K
W
N
E
E
I
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510756
1084
124281
S251
P
L
H
F
T
Y
S
S
C
P
E
G
A
R
Q
Chicken
Gallus gallus
NP_001026138
1084
124128
S251
P
L
H
F
T
Y
S
S
C
P
E
G
A
R
Q
Frog
Xenopus laevis
Q6DCL5
944
106566
L184
K
T
T
V
L
C
L
L
D
S
G
A
D
I
N
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611896
1122
128925
G248
A
K
R
A
S
A
G
G
Q
M
S
S
M
S
M
Honey Bee
Apis mellifera
XP_396547
1033
119022
S244
E
L
C
R
S
I
L
S
P
K
M
S
D
A
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797123
1037
118587
Q248
F
L
I
P
A
L
A
Q
R
E
G
G
I
P
P
Poplar Tree
Populus trichocarpa
XP_002314972
1027
117409
S240
D
N
S
I
R
N
A
S
P
L
E
R
I
L
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
L241
M
T
G
N
I
L
S
L
E
R
V
L
I
L
I
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
L150
V
D
E
F
L
D
S
L
S
V
Y
L
C
R
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
N.A.
95.4
N.A.
93.3
22.1
N.A.
91.4
90.6
22.8
22.5
N.A.
39.7
43
N.A.
44.2
Protein Similarity:
100
98.1
N.A.
97.4
N.A.
97.2
38.4
N.A.
95.6
94.8
39
38.3
N.A.
61
62.7
N.A.
61.6
P-Site Identity:
100
100
N.A.
100
N.A.
73.3
6.6
N.A.
93.3
93.3
0
0
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
6.6
N.A.
100
100
0
0
N.A.
6.6
20
N.A.
13.3
Percent
Protein Identity:
28.3
N.A.
N.A.
28.7
26.7
N.A.
Protein Similarity:
47
N.A.
N.A.
49
44.9
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
7
14
0
0
0
0
14
34
7
14
% A
% Cys:
0
0
7
0
0
7
0
0
40
0
0
0
7
0
0
% C
% Asp:
7
7
0
0
0
7
0
0
7
0
0
0
14
0
0
% D
% Glu:
7
0
7
0
0
0
0
0
7
7
54
7
0
0
0
% E
% Phe:
7
0
0
47
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
7
0
0
0
7
7
0
0
14
40
0
0
0
% G
% His:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
7
7
7
7
0
0
0
0
0
0
27
7
7
% I
% Lys:
7
14
7
0
0
0
0
7
0
7
0
0
0
0
0
% K
% Leu:
0
54
0
0
20
14
14
20
0
7
0
14
0
20
0
% L
% Met:
7
0
0
0
0
0
0
0
0
7
7
0
7
0
7
% M
% Asn:
0
7
0
7
0
14
20
0
0
7
0
0
0
0
7
% N
% Pro:
40
0
0
7
0
0
7
0
14
40
0
0
0
7
7
% P
% Gln:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
34
% Q
% Arg:
0
0
7
7
7
0
0
0
7
7
0
7
0
47
0
% R
% Ser:
0
0
7
7
14
0
34
54
7
7
7
14
7
7
0
% S
% Thr:
0
14
7
0
40
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
7
0
0
0
0
0
7
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
40
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _