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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNPS1 All Species: 14.85
Human Site: S251 Identified Species: 27.22
UniProt: Q15287 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15287 NP_006702.1 305 34208 S251 R P P P R R F S P P R R M L P
Chimpanzee Pan troglodytes Q5R1W5 221 25469 R168 S K S R S A R R S K S K S S S
Rhesus Macaque Macaca mulatta XP_001084468 530 57943 S476 R P P P R R F S P P R R M L P
Dog Lupus familis XP_864742 274 30100 L221 P D E A E K A L K H M D G G Q
Cat Felis silvestris
Mouse Mus musculus Q8VE97 489 55961 S417 R E H A K A E S G Q R G S R A
Rat Rattus norvegicus Q6AYK1 305 34220 S251 R P P P R R F S P P R R M L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514313 197 21279 K144 R S K S K L P K R D E K E R K
Chicken Gallus gallus P30352 221 25506 R168 S K S R S A R R S K S K S S S
Frog Xenopus laevis Q5XG24 283 31787 P230 P M P R R F S P P R R M L P P
Zebra Danio Brachydanio rerio Q6PG31 283 31721 R230 P R R L S P P R R M P P P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649903 374 41830 S309 R P P M R R P S P P M R R P Q
Honey Bee Apis mellifera XP_624099 326 37181 M256 R P L P M R R M S P L M G R R
Nematode Worm Caenorhab. elegans Q09511 196 22569 S143 R S R S R T R S P P S R D R R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.3 55.6 67.5 N.A. 24.1 99.6 N.A. 57 20 80.3 75.7 N.A. 38.7 39.8 21.9 N.A.
Protein Similarity: 100 32.7 56.9 72.7 N.A. 33.9 99.6 N.A. 61.6 32.4 86.8 84.9 N.A. 51 51.5 32.4 N.A.
P-Site Identity: 100 0 100 0 N.A. 20 100 N.A. 6.6 0 33.3 6.6 N.A. 60 33.3 40 N.A.
P-Site Similarity: 100 6.6 100 6.6 N.A. 26.6 100 N.A. 20 6.6 40 6.6 N.A. 60 33.3 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 24 8 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 8 0 8 8 0 0 % D
% Glu: 0 8 8 0 8 0 8 0 0 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 8 24 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 8 16 8 0 % G
% His: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 16 8 0 16 8 0 8 8 16 0 24 0 0 8 % K
% Leu: 0 0 8 8 0 8 0 8 0 0 8 0 8 24 0 % L
% Met: 0 8 0 8 8 0 0 8 0 8 16 16 24 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 24 39 39 31 0 8 24 8 47 47 8 8 8 24 39 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 16 % Q
% Arg: 62 8 16 24 47 39 31 24 16 8 39 39 8 31 16 % R
% Ser: 16 16 16 16 24 0 8 47 24 0 24 0 24 16 16 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _