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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP2
All Species:
19.39
Human Site:
Y280
Identified Species:
38.79
UniProt:
Q15269
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15269
NP_005040.2
919
102452
Y280
K
Y
S
R
L
A
K
Y
F
F
N
K
E
G
D
Chimpanzee
Pan troglodytes
XP_531577
919
102478
Y280
K
Y
S
R
L
A
K
Y
F
F
N
K
E
G
D
Rhesus Macaque
Macaca mulatta
XP_001118393
1042
115164
Y403
K
Y
S
R
L
A
K
Y
F
F
N
K
E
G
D
Dog
Lupus familis
XP_544915
883
97950
A259
D
F
N
K
L
T
A
A
A
Y
H
K
K
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU03
919
102891
Y280
K
Y
S
R
L
A
K
Y
F
L
N
K
E
G
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512293
921
103526
Y286
K
Y
R
R
A
A
K
Y
F
F
N
K
E
G
D
Chicken
Gallus gallus
XP_416757
641
71915
A23
F
N
N
L
T
S
A
A
Y
H
K
K
T
H
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623489
886
99963
V260
K
E
K
T
D
K
Q
V
K
A
Y
E
Y
N
L
Nematode Worm
Caenorhab. elegans
P91341
910
102179
S265
K
T
K
K
Y
W
L
S
E
S
S
G
S
G
K
Sea Urchin
Strong. purpuratus
XP_001175743
916
101911
H269
K
Y
K
R
I
A
K
H
Y
Y
N
K
S
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25635
923
103965
K252
K
Y
S
W
R
I
T
K
K
H
F
F
Y
A
N
Red Bread Mold
Neurospora crassa
Q9C270
899
99686
S266
C
A
A
F
H
P
E
S
N
L
L
V
A
G
F
Conservation
Percent
Protein Identity:
100
99.7
87
84.5
N.A.
89.3
N.A.
N.A.
77.8
54.7
N.A.
N.A.
N.A.
N.A.
49.5
38
57.1
Protein Similarity:
100
99.8
87.5
90.5
N.A.
95.7
N.A.
N.A.
88.5
62.6
N.A.
N.A.
N.A.
N.A.
70.6
60.5
74.6
P-Site Identity:
100
100
100
13.3
N.A.
93.3
N.A.
N.A.
86.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
13.3
60
P-Site Similarity:
100
100
100
53.3
N.A.
93.3
N.A.
N.A.
86.6
26.6
N.A.
N.A.
N.A.
N.A.
20
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.9
42.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.8
62.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
9
50
17
17
9
9
0
0
9
9
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
50
% D
% Glu:
0
9
0
0
0
0
9
0
9
0
0
9
42
0
0
% E
% Phe:
9
9
0
9
0
0
0
0
42
34
9
9
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
67
0
% G
% His:
0
0
0
0
9
0
0
9
0
17
9
0
0
9
9
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
75
0
25
17
0
9
50
9
17
0
9
67
9
0
9
% K
% Leu:
0
0
0
9
42
0
9
0
0
17
9
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
17
0
0
0
0
0
9
0
50
0
0
9
9
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
50
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
42
0
0
9
0
17
0
9
9
0
17
0
0
% S
% Thr:
0
9
0
9
9
9
9
0
0
0
0
0
9
9
0
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
59
0
0
9
0
0
42
17
17
9
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _