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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP2
All Species:
23.33
Human Site:
Y274
Identified Species:
46.67
UniProt:
Q15269
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15269
NP_005040.2
919
102452
Y274
E
K
T
G
K
V
K
Y
S
R
L
A
K
Y
F
Chimpanzee
Pan troglodytes
XP_531577
919
102478
Y274
E
K
T
G
K
V
K
Y
S
R
L
A
K
Y
F
Rhesus Macaque
Macaca mulatta
XP_001118393
1042
115164
Y397
E
K
T
G
K
V
K
Y
S
R
L
A
K
Y
F
Dog
Lupus familis
XP_544915
883
97950
F253
F
F
N
K
E
G
D
F
N
K
L
T
A
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU03
919
102891
Y274
E
R
V
G
K
V
K
Y
S
R
L
A
K
Y
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512293
921
103526
Y280
E
K
K
G
K
V
K
Y
R
R
A
A
K
Y
F
Chicken
Gallus gallus
XP_416757
641
71915
N17
F
N
K
E
G
D
F
N
N
L
T
S
A
A
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623489
886
99963
E254
I
N
I
E
K
A
K
E
K
T
D
K
Q
V
K
Nematode Worm
Caenorhab. elegans
P91341
910
102179
T259
E
K
I
F
F
E
K
T
K
K
Y
W
L
S
E
Sea Urchin
Strong. purpuratus
XP_001175743
916
101911
Y263
E
K
Q
N
K
I
K
Y
K
R
I
A
K
H
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25635
923
103965
Y246
E
E
V
D
I
S
K
Y
S
W
R
I
T
K
K
Red Bread Mold
Neurospora crassa
Q9C270
899
99686
A260
N
S
A
T
V
R
C
A
A
F
H
P
E
S
N
Conservation
Percent
Protein Identity:
100
99.7
87
84.5
N.A.
89.3
N.A.
N.A.
77.8
54.7
N.A.
N.A.
N.A.
N.A.
49.5
38
57.1
Protein Similarity:
100
99.8
87.5
90.5
N.A.
95.7
N.A.
N.A.
88.5
62.6
N.A.
N.A.
N.A.
N.A.
70.6
60.5
74.6
P-Site Identity:
100
100
100
6.6
N.A.
86.6
N.A.
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
13.3
20
53.3
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
N.A.
N.A.
80
20
N.A.
N.A.
N.A.
N.A.
20
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.9
42.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.8
62.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
9
9
0
9
50
17
17
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
9
9
0
0
0
9
0
0
0
0
% D
% Glu:
67
9
0
17
9
9
0
9
0
0
0
0
9
0
9
% E
% Phe:
17
9
0
9
9
0
9
9
0
9
0
0
0
0
42
% F
% Gly:
0
0
0
42
9
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% H
% Ile:
9
0
17
0
9
9
0
0
0
0
9
9
0
0
0
% I
% Lys:
0
50
17
9
59
0
75
0
25
17
0
9
50
9
17
% K
% Leu:
0
0
0
0
0
0
0
0
0
9
42
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
17
9
9
0
0
0
9
17
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
9
0
0
0
9
0
0
9
50
9
0
0
0
0
% R
% Ser:
0
9
0
0
0
9
0
0
42
0
0
9
0
17
0
% S
% Thr:
0
0
25
9
0
0
0
9
0
9
9
9
9
0
0
% T
% Val:
0
0
17
0
9
42
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
9
0
0
42
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _