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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP2
All Species:
20.61
Human Site:
Y181
Identified Species:
41.21
UniProt:
Q15269
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15269
NP_005040.2
919
102452
Y181
E
R
W
D
N
L
I
Y
Y
A
L
G
G
H
K
Chimpanzee
Pan troglodytes
XP_531577
919
102478
Y181
E
R
W
D
N
L
I
Y
Y
A
L
G
G
H
K
Rhesus Macaque
Macaca mulatta
XP_001118393
1042
115164
Y304
E
R
W
D
N
L
I
Y
Y
A
L
G
G
H
K
Dog
Lupus familis
XP_544915
883
97950
Q182
D
G
A
L
C
V
W
Q
C
D
T
P
P
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU03
919
102891
Y181
E
R
W
D
N
L
I
Y
Y
A
L
S
G
H
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512293
921
103526
Y181
K
R
W
T
N
L
I
Y
Y
S
L
G
G
H
K
Chicken
Gallus gallus
XP_416757
641
71915
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623489
886
99963
Y182
E
K
Y
E
N
F
R
Y
I
N
L
G
G
H
S
Nematode Worm
Caenorhab. elegans
P91341
910
102179
I183
K
D
F
K
N
L
F
I
H
P
L
A
S
H
K
Sea Urchin
Strong. purpuratus
XP_001175743
916
101911
V182
D
D
M
D
H
L
I
V
Y
S
L
A
G
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25635
923
103965
V175
L
S
A
K
I
W
S
V
D
S
E
E
K
N
L
Red Bread Mold
Neurospora crassa
Q9C270
899
99686
P188
D
Q
E
E
G
F
T
P
T
V
L
S
G
H
R
Conservation
Percent
Protein Identity:
100
99.7
87
84.5
N.A.
89.3
N.A.
N.A.
77.8
54.7
N.A.
N.A.
N.A.
N.A.
49.5
38
57.1
Protein Similarity:
100
99.8
87.5
90.5
N.A.
95.7
N.A.
N.A.
88.5
62.6
N.A.
N.A.
N.A.
N.A.
70.6
60.5
74.6
P-Site Identity:
100
100
100
0
N.A.
93.3
N.A.
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
46.6
33.3
53.3
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
N.A.
N.A.
93.3
0
N.A.
N.A.
N.A.
N.A.
66.6
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.9
42.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.8
62.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
0
34
0
17
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
25
17
0
42
0
0
0
0
9
9
0
0
0
0
0
% D
% Glu:
42
0
9
17
0
0
0
0
0
0
9
9
0
9
0
% E
% Phe:
0
0
9
0
0
17
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
9
0
0
0
0
0
0
42
67
0
9
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
0
0
75
0
% H
% Ile:
0
0
0
0
9
0
50
9
9
0
0
0
0
0
0
% I
% Lys:
17
9
0
17
0
0
0
0
0
0
0
0
9
0
59
% K
% Leu:
9
0
0
9
0
59
0
0
0
0
75
0
0
0
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
59
0
0
0
0
9
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
9
0
9
9
0
0
% P
% Gln:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
42
0
0
0
0
9
0
0
0
0
0
0
0
9
% R
% Ser:
0
9
0
0
0
0
9
0
0
25
0
17
9
0
9
% S
% Thr:
0
0
0
9
0
0
9
0
9
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
17
0
9
0
0
0
0
0
% V
% Trp:
0
0
42
0
0
9
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
50
50
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _