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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PWP2 All Species: 17.88
Human Site: S902 Identified Species: 35.76
UniProt: Q15269 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15269 NP_005040.2 919 102452 S902 A E A S E D D S L H L L G G G
Chimpanzee Pan troglodytes XP_531577 919 102478 S902 A E A S E D D S L H L L G G G
Rhesus Macaque Macaca mulatta XP_001118393 1042 115164 S1025 E E A S E D D S L H L L G G G
Dog Lupus familis XP_544915 883 97950 T867 A D P S D D D T L H L L G G G
Cat Felis silvestris
Mouse Mus musculus Q8BU03 919 102891 S902 S D A S D E D S L H L L R A A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512293 921 103526 L904 E T P E P G G L Q P G E E D V
Chicken Gallus gallus XP_416757 641 71915 S625 V D E E D L E S D S D Y L M Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623489 886 99963 Q865 P K I N A A L Q M P I L L M L
Nematode Worm Caenorhab. elegans P91341 910 102179 I890 D E S D D E D I E D E S A G S
Sea Urchin Strong. purpuratus XP_001175743 916 101911 E892 D K D S E E E E I M S L R E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25635 923 103965 E878 D A D E D N E E N E E N D V V
Red Bread Mold Neurospora crassa Q9C270 899 99686 P872 T T G S D E Q P G A G G M S L
Conservation
Percent
Protein Identity: 100 99.7 87 84.5 N.A. 89.3 N.A. N.A. 77.8 54.7 N.A. N.A. N.A. N.A. 49.5 38 57.1
Protein Similarity: 100 99.8 87.5 90.5 N.A. 95.7 N.A. N.A. 88.5 62.6 N.A. N.A. N.A. N.A. 70.6 60.5 74.6
P-Site Identity: 100 100 93.3 73.3 N.A. 53.3 N.A. N.A. 0 6.6 N.A. N.A. N.A. N.A. 6.6 20 20
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 N.A. N.A. 0 26.6 N.A. N.A. N.A. N.A. 33.3 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.9 42.7
Protein Similarity: N.A. N.A. N.A. N.A. 62.8 62.1
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 34 0 9 9 0 0 0 9 0 0 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 25 17 9 50 34 50 0 9 9 9 0 9 9 0 % D
% Glu: 17 34 9 25 34 34 25 17 9 9 17 9 9 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 9 9 0 9 0 17 9 34 42 34 % G
% His: 0 0 0 0 0 0 0 0 0 42 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 9 9 0 9 0 0 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 9 9 9 42 0 42 59 17 0 17 % L
% Met: 0 0 0 0 0 0 0 0 9 9 0 0 9 17 0 % M
% Asn: 0 0 0 9 0 9 0 0 9 0 0 9 0 0 0 % N
% Pro: 9 0 17 0 9 0 0 9 0 17 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 9 9 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % R
% Ser: 9 0 9 59 0 0 0 42 0 9 9 9 0 9 9 % S
% Thr: 9 17 0 0 0 0 0 9 0 0 0 0 0 0 0 % T
% Val: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _