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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PWP2 All Species: 28.79
Human Site: S792 Identified Species: 57.58
UniProt: Q15269 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15269 NP_005040.2 919 102452 S792 G E I E V V T S S L P E L Y V
Chimpanzee Pan troglodytes XP_531577 919 102478 S792 G E I E V V T S S L P E L Y V
Rhesus Macaque Macaca mulatta XP_001118393 1042 115164 S915 G E I E V V T S S L P E L Y V
Dog Lupus familis XP_544915 883 97950 S757 D E V E V V S S S L P D L Y V
Cat Felis silvestris
Mouse Mus musculus Q8BU03 919 102891 T792 N E I E V V S T S L P E L Y V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512293 921 103526 E794 S V P R N E I E V V C S S L P
Chicken Gallus gallus XP_416757 641 71915 V515 E A I P G N E V D V V C S S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623489 886 99963 S755 T E G L L L Y S L D I G L T F
Nematode Worm Caenorhab. elegans P91341 910 102179 S780 S Q I P L V A S S L P L M Y A
Sea Urchin Strong. purpuratus XP_001175743 916 101911 S782 P Q V D V I C S S I A D T Y V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25635 923 103965 S768 K E I P L V A S N I P A I Y L
Red Bread Mold Neurospora crassa Q9C270 899 99686 E762 T D I P L V V E Q F P N V Y V
Conservation
Percent
Protein Identity: 100 99.7 87 84.5 N.A. 89.3 N.A. N.A. 77.8 54.7 N.A. N.A. N.A. N.A. 49.5 38 57.1
Protein Similarity: 100 99.8 87.5 90.5 N.A. 95.7 N.A. N.A. 88.5 62.6 N.A. N.A. N.A. N.A. 70.6 60.5 74.6
P-Site Identity: 100 100 100 73.3 N.A. 80 N.A. N.A. 0 6.6 N.A. N.A. N.A. N.A. 20 46.6 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 6.6 20 N.A. N.A. N.A. N.A. 33.3 66.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.9 42.7
Protein Similarity: N.A. N.A. N.A. N.A. 62.8 62.1
P-Site Identity: N.A. N.A. N.A. N.A. 40 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 17 0 0 0 9 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 9 9 0 0 0 % C
% Asp: 9 9 0 9 0 0 0 0 9 9 0 17 0 0 0 % D
% Glu: 9 59 0 42 0 9 9 17 0 0 0 34 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % F
% Gly: 25 0 9 0 9 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 67 0 0 9 9 0 0 17 9 0 9 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 34 9 0 0 9 50 0 9 50 9 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 9 0 0 0 9 9 0 0 9 0 0 9 0 0 0 % N
% Pro: 9 0 9 34 0 0 0 0 0 0 67 0 0 0 9 % P
% Gln: 0 17 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 0 0 0 0 0 17 67 59 0 0 9 17 9 0 % S
% Thr: 17 0 0 0 0 0 25 9 0 0 0 0 9 9 0 % T
% Val: 0 9 17 0 50 67 9 9 9 17 9 0 9 0 59 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 75 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _