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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWP2
All Species:
17.27
Human Site:
S375
Identified Species:
34.55
UniProt:
Q15269
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15269
NP_005040.2
919
102452
S375
K
Q
Q
G
H
F
N
S
M
V
A
L
A
Y
S
Chimpanzee
Pan troglodytes
XP_531577
919
102478
S375
K
Q
Q
G
H
F
N
S
M
V
A
L
A
Y
S
Rhesus Macaque
Macaca mulatta
XP_001118393
1042
115164
S498
K
Q
Q
G
H
F
N
S
M
V
T
L
A
Y
S
Dog
Lupus familis
XP_544915
883
97950
V354
S
P
D
G
Q
Y
I
V
T
G
G
D
D
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU03
919
102891
S375
K
Q
Q
G
H
F
N
S
M
V
A
L
A
Y
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512293
921
103526
N381
K
Q
Q
G
H
F
N
N
M
T
S
L
A
Y
S
Chicken
Gallus gallus
XP_416757
641
71915
V117
S
P
D
G
Q
Y
I
V
T
G
G
E
D
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623489
886
99963
I356
L
S
I
S
N
Q
C
I
T
S
I
A
I
N
S
Nematode Worm
Caenorhab. elegans
P91341
910
102179
R362
K
Q
Q
A
H
S
L
R
I
T
T
A
E
Y
S
Sea Urchin
Strong. purpuratus
XP_001175743
916
101911
N364
K
Q
Q
G
H
F
N
N
M
T
C
V
D
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25635
923
103965
S347
K
Q
Q
G
H
F
D
S
T
N
S
L
A
Y
S
Red Bread Mold
Neurospora crassa
Q9C270
899
99686
D360
R
I
V
T
V
A
D
D
G
K
I
K
V
W
D
Conservation
Percent
Protein Identity:
100
99.7
87
84.5
N.A.
89.3
N.A.
N.A.
77.8
54.7
N.A.
N.A.
N.A.
N.A.
49.5
38
57.1
Protein Similarity:
100
99.8
87.5
90.5
N.A.
95.7
N.A.
N.A.
88.5
62.6
N.A.
N.A.
N.A.
N.A.
70.6
60.5
74.6
P-Site Identity:
100
100
93.3
6.6
N.A.
100
N.A.
N.A.
80
6.6
N.A.
N.A.
N.A.
N.A.
6.6
40
66.6
P-Site Similarity:
100
100
93.3
13.3
N.A.
100
N.A.
N.A.
93.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
46.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.9
42.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.8
62.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
0
0
25
17
50
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
17
9
0
0
0
9
25
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
75
0
0
0
0
9
17
17
0
0
17
0
% G
% His:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
17
9
9
0
17
0
9
0
0
% I
% Lys:
67
0
0
0
0
0
0
0
0
9
0
9
0
0
17
% K
% Leu:
9
0
0
0
0
0
9
0
0
0
0
50
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
50
17
0
9
0
0
0
9
0
% N
% Pro:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
67
67
0
17
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
17
9
0
9
0
9
0
42
0
9
17
0
0
0
75
% S
% Thr:
0
0
0
9
0
0
0
0
34
25
17
0
0
0
0
% T
% Val:
0
0
9
0
9
0
0
17
0
34
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
17
0
0
0
0
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _