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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R4
All Species:
6.67
Human Site:
T32
Identified Species:
11.28
UniProt:
Q15257
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15257
NP_066954.2
358
40668
T32
I
P
K
K
E
I
H
T
V
P
D
M
G
K
W
Chimpanzee
Pan troglodytes
XP_001163459
373
41748
G30
E
P
G
R
G
R
V
G
A
R
V
K
G
E
R
Rhesus Macaque
Macaca mulatta
XP_001108890
359
40767
T32
I
P
K
K
E
I
H
T
V
P
D
M
G
K
W
Dog
Lupus familis
XP_548424
349
39477
R29
C
A
C
S
Q
L
P
R
T
N
M
A
A
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P58389
323
36692
E29
N
F
I
I
P
K
K
E
I
H
T
V
P
D
M
Rat
Rattus norvegicus
NP_001102047
323
36599
E29
T
F
I
I
P
K
K
E
I
H
T
V
P
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508723
358
40562
T34
S
E
Y
G
E
P
I
T
A
A
K
G
V
F
F
Chicken
Gallus gallus
NP_001026542
321
36721
E28
S
F
M
I
P
R
K
E
I
N
M
V
S
D
M
Frog
Xenopus laevis
NP_001089500
323
36857
K28
G
H
T
F
I
V
P
K
K
E
I
N
M
V
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523466
398
44238
F34
V
W
Q
K
S
R
A
F
H
D
L
I
G
Y
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784258
466
51558
I91
L
V
M
G
D
G
R
I
M
T
E
Q
F
E
Y
Poplar Tree
Populus trichocarpa
XP_002307365
396
45132
G30
S
P
T
C
V
K
C
G
G
P
C
S
F
P
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40454
393
45064
S31
Q
T
T
L
D
F
Q
S
S
L
A
I
H
R
I
Red Bread Mold
Neurospora crassa
Q7SEF9
449
50080
P41
P
N
L
R
D
R
I
P
K
L
E
P
R
R
R
Conservation
Percent
Protein Identity:
100
72.1
93.3
73.4
N.A.
86.8
85.7
N.A.
68.7
81.2
76.2
N.A.
N.A.
41.2
N.A.
N.A.
39
Protein Similarity:
100
76.9
96
77.3
N.A.
89.6
89.1
N.A.
75.9
85.1
82.6
N.A.
N.A.
56
N.A.
N.A.
50.4
P-Site Identity:
100
13.3
100
0
N.A.
0
0
N.A.
13.3
0
0
N.A.
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
13.3
N.A.
13.3
13.3
N.A.
20
13.3
6.6
N.A.
N.A.
33.3
N.A.
N.A.
40
Percent
Protein Identity:
38.3
N.A.
N.A.
N.A.
36.1
30.2
Protein Similarity:
56.8
N.A.
N.A.
N.A.
50.3
43.8
P-Site Identity:
13.3
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
0
15
8
8
8
8
8
0
% A
% Cys:
8
0
8
8
0
0
8
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
22
0
0
0
0
8
15
0
0
22
0
% D
% Glu:
8
8
0
0
22
0
0
22
0
8
15
0
0
15
0
% E
% Phe:
0
22
0
8
0
8
0
8
0
0
0
0
15
8
8
% F
% Gly:
8
0
8
15
8
8
0
15
8
0
0
8
29
0
0
% G
% His:
0
8
0
0
0
0
15
0
8
15
0
0
8
0
0
% H
% Ile:
15
0
15
22
8
15
15
8
22
0
8
15
0
0
15
% I
% Lys:
0
0
15
22
0
22
22
8
15
0
8
8
0
15
0
% K
% Leu:
8
0
8
8
0
8
0
0
0
15
8
0
0
0
0
% L
% Met:
0
0
15
0
0
0
0
0
8
0
15
15
8
0
22
% M
% Asn:
8
8
0
0
0
0
0
0
0
15
0
8
0
0
0
% N
% Pro:
8
29
0
0
22
8
15
8
0
22
0
8
15
8
15
% P
% Gln:
8
0
8
0
8
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
15
0
29
8
8
0
8
0
0
8
15
15
% R
% Ser:
22
0
0
8
8
0
0
8
8
0
0
8
8
0
8
% S
% Thr:
8
8
22
0
0
0
0
22
8
8
15
0
0
0
0
% T
% Val:
8
8
0
0
8
8
8
0
15
0
8
22
8
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
15
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _