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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R4
All Species:
24.85
Human Site:
T300
Identified Species:
42.05
UniProt:
Q15257
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15257
NP_066954.2
358
40668
T300
L
F
I
T
E
M
K
T
G
P
F
A
E
H
S
Chimpanzee
Pan troglodytes
XP_001163459
373
41748
T315
L
F
I
T
E
M
K
T
G
P
F
A
E
H
S
Rhesus Macaque
Macaca mulatta
XP_001108890
359
40767
T301
K
S
F
V
T
M
K
T
G
P
F
A
E
H
S
Dog
Lupus familis
XP_548424
349
39477
T291
L
F
I
T
E
M
K
T
G
P
F
A
E
H
S
Cat
Felis silvestris
Mouse
Mus musculus
P58389
323
36692
F268
T
E
M
K
T
G
P
F
A
E
H
S
N
Q
L
Rat
Rattus norvegicus
NP_001102047
323
36599
F268
T
E
M
K
T
G
P
F
A
E
H
S
N
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508723
358
40562
T301
L
F
I
T
Q
M
K
T
G
P
F
A
E
H
S
Chicken
Gallus gallus
NP_001026542
321
36721
F267
T
E
M
K
T
G
P
F
A
E
H
S
N
Q
L
Frog
Xenopus laevis
NP_001089500
323
36857
T266
L
F
I
T
E
M
K
T
G
P
F
A
E
H
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523466
398
44238
Q296
L
S
K
F
P
V
I
Q
H
V
Y
F
G
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784258
466
51558
T374
D
F
I
N
R
M
K
T
G
P
F
A
E
H
S
Poplar Tree
Populus trichocarpa
XP_002307365
396
45132
K334
L
L
I
K
K
V
K
K
G
L
F
A
E
H
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40454
393
45064
K298
Y
S
V
E
V
L
K
K
F
P
V
V
Q
H
F
Red Bread Mold
Neurospora crassa
Q7SEF9
449
50080
V322
F
V
N
S
T
K
T
V
K
G
L
R
W
H
S
Conservation
Percent
Protein Identity:
100
72.1
93.3
73.4
N.A.
86.8
85.7
N.A.
68.7
81.2
76.2
N.A.
N.A.
41.2
N.A.
N.A.
39
Protein Similarity:
100
76.9
96
77.3
N.A.
89.6
89.1
N.A.
75.9
85.1
82.6
N.A.
N.A.
56
N.A.
N.A.
50.4
P-Site Identity:
100
100
66.6
100
N.A.
0
0
N.A.
93.3
0
100
N.A.
N.A.
6.6
N.A.
N.A.
80
P-Site Similarity:
100
100
66.6
100
N.A.
13.3
13.3
N.A.
100
13.3
100
N.A.
N.A.
20
N.A.
N.A.
80
Percent
Protein Identity:
38.3
N.A.
N.A.
N.A.
36.1
30.2
Protein Similarity:
56.8
N.A.
N.A.
N.A.
50.3
43.8
P-Site Identity:
60
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
22
0
0
58
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
22
0
8
29
0
0
0
0
22
0
0
58
8
0
% E
% Phe:
8
43
8
8
0
0
0
22
8
0
58
8
0
0
8
% F
% Gly:
0
0
0
0
0
22
0
0
58
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
22
0
0
72
0
% H
% Ile:
0
0
50
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
29
8
8
65
15
8
0
0
0
0
0
0
% K
% Leu:
50
8
0
0
0
8
0
0
0
8
8
0
0
0
29
% L
% Met:
0
0
22
0
0
50
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
22
0
0
% N
% Pro:
0
0
0
0
8
0
22
0
0
58
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
8
22
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
22
0
8
0
0
0
0
0
0
0
22
0
0
65
% S
% Thr:
22
0
0
36
36
0
8
50
0
0
0
0
0
0
0
% T
% Val:
0
8
8
8
8
15
0
8
0
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _