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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R4
All Species:
10
Human Site:
T20
Identified Species:
16.92
UniProt:
Q15257
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15257
NP_066954.2
358
40668
T20
S
E
E
A
P
P
A
T
Q
N
F
I
I
P
K
Chimpanzee
Pan troglodytes
XP_001163459
373
41748
S18
A
H
L
S
S
G
S
S
E
P
L
V
E
P
G
Rhesus Macaque
Macaca mulatta
XP_001108890
359
40767
T20
S
E
E
A
P
P
A
T
Q
N
F
I
I
P
K
Dog
Lupus familis
XP_548424
349
39477
R17
G
R
W
L
L
G
R
R
A
G
R
W
C
A
C
Cat
Felis silvestris
Mouse
Mus musculus
P58389
323
36692
P17
P
D
S
S
E
E
T
P
P
T
T
Q
N
F
I
Rat
Rattus norvegicus
NP_001102047
323
36599
P17
P
D
S
S
E
E
T
P
S
A
T
P
T
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508723
358
40562
S22
W
A
G
N
A
A
K
S
N
P
S
A
S
E
Y
Chicken
Gallus gallus
NP_001026542
321
36721
P16
G
N
S
E
E
M
A
P
P
L
Q
Q
S
F
M
Frog
Xenopus laevis
NP_001089500
323
36857
P16
D
H
A
E
D
E
I
P
P
S
L
V
G
H
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523466
398
44238
L22
I
A
K
K
V
Q
N
L
G
D
M
G
V
W
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784258
466
51558
T79
G
I
F
D
S
D
M
T
K
E
T
R
L
V
M
Poplar Tree
Populus trichocarpa
XP_002307365
396
45132
S18
H
Q
D
P
P
K
S
S
T
A
P
L
S
P
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40454
393
45064
R19
T
F
S
T
P
V
K
R
I
F
D
T
Q
T
T
Red Bread Mold
Neurospora crassa
Q7SEF9
449
50080
A29
S
G
Q
P
I
S
K
A
G
Q
A
I
P
N
L
Conservation
Percent
Protein Identity:
100
72.1
93.3
73.4
N.A.
86.8
85.7
N.A.
68.7
81.2
76.2
N.A.
N.A.
41.2
N.A.
N.A.
39
Protein Similarity:
100
76.9
96
77.3
N.A.
89.6
89.1
N.A.
75.9
85.1
82.6
N.A.
N.A.
56
N.A.
N.A.
50.4
P-Site Identity:
100
6.6
100
0
N.A.
0
0
N.A.
0
6.6
0
N.A.
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
46.6
100
0
N.A.
13.3
13.3
N.A.
6.6
6.6
13.3
N.A.
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
38.3
N.A.
N.A.
N.A.
36.1
30.2
Protein Similarity:
56.8
N.A.
N.A.
N.A.
50.3
43.8
P-Site Identity:
13.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
15
8
8
22
8
8
15
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
8
15
8
8
8
8
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
15
15
15
22
22
0
0
8
8
0
0
8
8
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
8
15
0
0
22
0
% F
% Gly:
22
8
8
0
0
15
0
0
15
8
0
8
8
0
8
% G
% His:
8
15
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
8
0
0
8
0
8
0
8
0
0
22
15
0
15
% I
% Lys:
0
0
8
8
0
8
22
0
8
0
0
0
0
0
15
% K
% Leu:
0
0
8
8
8
0
0
8
0
8
15
8
8
0
8
% L
% Met:
0
0
0
0
0
8
8
0
0
0
8
0
0
0
15
% M
% Asn:
0
8
0
8
0
0
8
0
8
15
0
0
8
8
0
% N
% Pro:
15
0
0
15
29
15
0
29
22
15
8
8
8
29
0
% P
% Gln:
0
8
8
0
0
8
0
0
15
8
8
15
8
0
8
% Q
% Arg:
0
8
0
0
0
0
8
15
0
0
8
8
0
0
0
% R
% Ser:
22
0
29
22
15
8
15
22
8
8
8
0
22
0
0
% S
% Thr:
8
0
0
8
0
0
15
22
8
8
22
8
8
8
22
% T
% Val:
0
0
0
0
8
8
0
0
0
0
0
15
8
8
0
% V
% Trp:
8
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _