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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGES3
All Species:
25.15
Human Site:
S72
Identified Species:
46.11
UniProt:
Q15185
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15185
NP_006592.3
160
18697
S72
K
H
K
R
T
D
R
S
I
L
C
C
L
R
K
Chimpanzee
Pan troglodytes
XP_001159085
160
18695
S72
K
H
K
R
T
D
R
S
I
L
C
C
L
R
K
Rhesus Macaque
Macaca mulatta
XP_001115374
139
16458
N62
L
F
H
C
I
D
P
N
D
S
K
H
K
R
T
Dog
Lupus familis
XP_848910
500
54559
S412
K
H
K
R
T
D
R
S
I
L
C
C
L
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Q7
160
18703
S72
K
H
K
R
T
D
R
S
I
L
C
C
L
R
K
Rat
Rattus norvegicus
NP_001014294
149
17334
A69
I
L
C
C
L
R
K
A
E
S
D
H
S
W
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512870
235
26525
S144
K
H
K
R
T
D
R
S
I
L
C
C
L
R
K
Chicken
Gallus gallus
Q90955
146
16851
E67
L
C
C
L
R
K
G
E
S
G
Q
A
W
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998335
159
18446
S72
K
H
K
R
T
D
R
S
V
F
C
C
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH95
184
20734
C78
T
S
K
N
I
G
R
C
L
E
F
T
I
P
K
Honey Bee
Apis mellifera
XP_624846
176
20104
T78
I
Q
N
L
R
G
R
T
L
E
L
V
L
F
K
Nematode Worm
Caenorhab. elegans
Q23280
175
19413
R71
K
H
T
G
S
S
T
R
V
V
E
I
T
V
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28707
216
24063
Y90
K
V
A
N
G
Q
H
Y
F
L
K
L
Y
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.8
32
N.A.
98.7
81.8
N.A.
63.4
87.5
N.A.
79.3
N.A.
23.3
36.9
27.4
N.A.
Protein Similarity:
100
100
86.8
32
N.A.
100
85.6
N.A.
65.1
90
N.A.
90.6
N.A.
41.2
51.1
47.4
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
0
N.A.
100
0
N.A.
80
N.A.
20
20
13.3
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
13.3
N.A.
100
6.6
N.A.
93.3
N.A.
33.3
33.3
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% A
% Cys:
0
8
16
16
0
0
0
8
0
0
47
47
0
0
0
% C
% Asp:
0
0
0
0
0
54
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
16
8
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
8
8
0
0
8
0
% F
% Gly:
0
0
0
8
8
16
8
0
0
8
0
0
0
0
0
% G
% His:
0
54
8
0
0
0
8
0
0
0
0
16
0
0
0
% H
% Ile:
16
0
0
0
16
0
0
0
39
0
0
8
8
0
0
% I
% Lys:
62
0
54
0
0
8
8
0
0
0
16
0
8
16
70
% K
% Leu:
16
8
0
16
8
0
0
0
16
47
8
8
54
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
16
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
16
8
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
0
0
47
16
8
62
8
0
0
0
0
0
47
8
% R
% Ser:
0
8
0
0
8
8
0
47
8
16
0
0
8
0
0
% S
% Thr:
8
0
8
0
47
0
8
8
0
0
0
8
8
0
8
% T
% Val:
0
8
0
0
0
0
0
0
16
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _