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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGES3
All Species:
29.09
Human Site:
S148
Identified Species:
53.33
UniProt:
Q15185
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15185
NP_006592.3
160
18697
S148
V
D
G
A
D
D
D
S
Q
D
S
D
D
E
K
Chimpanzee
Pan troglodytes
XP_001159085
160
18695
S148
V
D
G
A
D
D
D
S
Q
D
S
D
D
E
K
Rhesus Macaque
Macaca mulatta
XP_001115374
139
16458
D129
R
F
S
E
D
S
Q
D
S
D
D
E
K
M
P
Dog
Lupus familis
XP_848910
500
54559
S488
V
D
G
A
D
D
D
S
Q
D
S
D
D
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Q7
160
18703
S148
V
D
G
A
D
D
D
S
Q
D
S
D
D
E
K
Rat
Rattus norvegicus
NP_001014294
149
17334
S137
V
D
G
A
D
D
D
S
Q
D
S
D
D
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512870
235
26525
S220
V
D
G
V
D
D
D
S
P
D
S
D
D
E
S
Chicken
Gallus gallus
Q90955
146
16851
S134
V
D
G
A
D
D
D
S
P
D
S
D
D
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998335
159
18446
S147
D
G
A
D
E
E
E
S
P
D
S
D
D
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH95
184
20734
G173
N
D
E
D
D
E
E
G
G
E
G
D
K
E
K
Honey Bee
Apis mellifera
XP_624846
176
20104
G163
E
L
G
D
E
G
E
G
M
D
S
D
D
D
D
Nematode Worm
Caenorhab. elegans
Q23280
175
19413
L161
E
D
D
D
M
P
D
L
E
D
N
E
E
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28707
216
24063
E203
G
D
F
K
E
N
D
E
E
D
E
E
E
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
86.8
32
N.A.
98.7
81.8
N.A.
63.4
87.5
N.A.
79.3
N.A.
23.3
36.9
27.4
N.A.
Protein Similarity:
100
100
86.8
32
N.A.
100
85.6
N.A.
65.1
90
N.A.
90.6
N.A.
41.2
51.1
47.4
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
80
93.3
N.A.
46.6
N.A.
33.3
33.3
26.6
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
80
93.3
N.A.
66.6
N.A.
53.3
53.3
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
47
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
77
8
31
70
54
70
8
0
93
8
77
70
8
8
% D
% Glu:
16
0
8
8
24
16
24
8
16
8
8
24
16
85
8
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
62
0
0
8
0
16
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
16
0
62
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
24
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
8
0
39
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
8
0
62
8
0
70
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
54
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _