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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5A All Species: 39.7
Human Site: Y215 Identified Species: 67.18
UniProt: Q15172 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15172 NP_006234.1 486 56194 Y215 K T V L H R I Y G K F L G L R
Chimpanzee Pan troglodytes XP_001151388 673 75031 Y441 K T V L H R I Y G K F L G L R
Rhesus Macaque Macaca mulatta XP_001106979 628 70785 Y375 K T V L H R I Y G K F L G L R
Dog Lupus familis XP_547400 566 64736 Y295 K T V L H R I Y G K F L G L R
Cat Felis silvestris
Mouse Mus musculus Q6PD03 486 56328 Y215 K T V L H R I Y G K F L G L R
Rat Rattus norvegicus NP_001101361 486 56318 Y215 K T V L H R I Y G K F L G M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509703 483 55774 Y211 K T V L H R I Y G K F L G L R
Chicken Gallus gallus XP_419432 476 55266 F208 L H R I Y G K F L G L R A F I
Frog Xenopus laevis NP_001086500 476 55192 A212 G K F L G L R A F I R K Q I N
Zebra Danio Brachydanio rerio XP_690932 478 56125 Y207 K T I L H R I Y G K F L G L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651569 524 59708 G207 R I Y G K F L G L R A F I R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137 F207 L H R I Y G K F L G L R A F I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 Y258 K T I L H R I Y G K F M V H R
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 Y439 K T T L H R I Y G K F L S L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.6 74.3 85.1 N.A. 97.7 97.9 N.A. 95 93.2 88 80 N.A. 66.7 N.A. N.A. 68.3
Protein Similarity: 100 66.1 74.5 85.1 N.A. 98.7 98.7 N.A. 97.5 95.8 94 88.8 N.A. 78 N.A. N.A. 78.8
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 100 0 6.6 93.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 20 13.3 100 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 48.2 37.5 N.A.
Protein Similarity: N.A. N.A. N.A. 65.2 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 86.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 8 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 8 0 15 8 0 72 8 0 15 0 % F
% Gly: 8 0 0 8 8 15 0 8 72 15 0 0 58 0 0 % G
% His: 0 15 0 0 72 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 15 15 0 0 72 0 0 8 0 0 8 8 15 % I
% Lys: 72 8 0 0 8 0 15 0 0 72 0 8 0 0 8 % K
% Leu: 15 0 0 79 0 8 8 0 22 0 15 65 0 58 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 8 0 15 0 0 72 8 0 0 8 8 15 0 8 72 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % S
% Thr: 0 72 8 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 50 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 15 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _