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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5A
All Species:
39.7
Human Site:
Y215
Identified Species:
67.18
UniProt:
Q15172
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15172
NP_006234.1
486
56194
Y215
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
Y441
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Rhesus Macaque
Macaca mulatta
XP_001106979
628
70785
Y375
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Dog
Lupus familis
XP_547400
566
64736
Y295
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
Y215
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Rat
Rattus norvegicus
NP_001101361
486
56318
Y215
K
T
V
L
H
R
I
Y
G
K
F
L
G
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509703
483
55774
Y211
K
T
V
L
H
R
I
Y
G
K
F
L
G
L
R
Chicken
Gallus gallus
XP_419432
476
55266
F208
L
H
R
I
Y
G
K
F
L
G
L
R
A
F
I
Frog
Xenopus laevis
NP_001086500
476
55192
A212
G
K
F
L
G
L
R
A
F
I
R
K
Q
I
N
Zebra Danio
Brachydanio rerio
XP_690932
478
56125
Y207
K
T
I
L
H
R
I
Y
G
K
F
L
G
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651569
524
59708
G207
R
I
Y
G
K
F
L
G
L
R
A
F
I
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
F207
L
H
R
I
Y
G
K
F
L
G
L
R
A
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
Y258
K
T
I
L
H
R
I
Y
G
K
F
M
V
H
R
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
Y439
K
T
T
L
H
R
I
Y
G
K
F
L
S
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.6
74.3
85.1
N.A.
97.7
97.9
N.A.
95
93.2
88
80
N.A.
66.7
N.A.
N.A.
68.3
Protein Similarity:
100
66.1
74.5
85.1
N.A.
98.7
98.7
N.A.
97.5
95.8
94
88.8
N.A.
78
N.A.
N.A.
78.8
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
0
6.6
93.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
13.3
100
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.2
37.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
49.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
86.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
8
0
15
8
0
72
8
0
15
0
% F
% Gly:
8
0
0
8
8
15
0
8
72
15
0
0
58
0
0
% G
% His:
0
15
0
0
72
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
15
15
0
0
72
0
0
8
0
0
8
8
15
% I
% Lys:
72
8
0
0
8
0
15
0
0
72
0
8
0
0
8
% K
% Leu:
15
0
0
79
0
8
8
0
22
0
15
65
0
58
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
15
0
0
72
8
0
0
8
8
15
0
8
72
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% S
% Thr:
0
72
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
50
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
15
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _