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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5A All Species: 40.3
Human Site: T434 Identified Species: 68.21
UniProt: Q15172 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15172 NP_006234.1 486 56194 T434 G K L F D D L T S S Y K A E R
Chimpanzee Pan troglodytes XP_001151388 673 75031 V641 N P T I V A L V Y N V L K T L
Rhesus Macaque Macaca mulatta XP_001106979 628 70785 T576 G K L F D D L T S S Y K A E R
Dog Lupus familis XP_547400 566 64736 T514 G K L F D D L T S S Y K A E R
Cat Felis silvestris
Mouse Mus musculus Q6PD03 486 56328 T434 G K L F D D L T S S Y K A E R
Rat Rattus norvegicus NP_001101361 486 56318 T434 G K L F D D L T S S Y K A E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509703 483 55774 T430 G K L F D D L T S S Y K A E R
Chicken Gallus gallus XP_419432 476 55266 T424 G K L F D E L T S S Y K A E R
Frog Xenopus laevis NP_001086500 476 55192 T423 G K L F D E L T S S Y K A E R
Zebra Danio Brachydanio rerio XP_690932 478 56125 T426 S K L F D E L T T S Y K S D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651569 524 59708 T421 S K L F D E L T S S Y K A E R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137 V401 D H W N Q T I V A L V Y N V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 L477 P E L F K E C L A K F K E D E
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 N684 P V L Y E N C N A L Y L S S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.6 74.3 85.1 N.A. 97.7 97.9 N.A. 95 93.2 88 80 N.A. 66.7 N.A. N.A. 68.3
Protein Similarity: 100 66.1 74.5 85.1 N.A. 98.7 98.7 N.A. 97.5 95.8 94 88.8 N.A. 78 N.A. N.A. 78.8
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 100 93.3 93.3 66.6 N.A. 86.6 N.A. N.A. 0
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 93.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 48.2 37.5 N.A.
Protein Similarity: N.A. N.A. N.A. 65.2 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 22 0 0 0 65 0 0 % A
% Cys: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 72 43 0 0 0 0 0 0 0 15 0 % D
% Glu: 0 8 0 0 8 36 0 0 0 0 0 0 8 65 8 % E
% Phe: 0 0 0 79 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 72 0 0 8 0 0 0 0 8 0 79 8 0 0 % K
% Leu: 0 0 86 0 0 0 79 8 0 15 0 15 0 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 8 0 8 0 8 0 0 8 0 0 % N
% Pro: 15 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 % R
% Ser: 15 0 0 0 0 0 0 0 65 72 0 0 15 8 0 % S
% Thr: 0 0 8 0 0 8 0 72 8 0 0 0 0 8 0 % T
% Val: 0 8 0 0 8 0 0 15 0 0 15 0 0 8 8 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 8 0 79 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _