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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP2R5A All Species: 26.67
Human Site: T305 Identified Species: 45.13
UniProt: Q15172 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15172 NP_006234.1 486 56194 T305 Q F L E K D T T L T E P V I R
Chimpanzee Pan troglodytes XP_001151388 673 75031 L513 H T A K G L A L F H A Q L A Y
Rhesus Macaque Macaca mulatta XP_001106979 628 70785 L447 H T A K G L A L F H A Q V I R
Dog Lupus familis XP_547400 566 64736 T385 Q F L E K D T T L T E P V I R
Cat Felis silvestris
Mouse Mus musculus Q6PD03 486 56328 T305 Q F L E K D T T L T E P V I R
Rat Rattus norvegicus NP_001101361 486 56318 T305 Q F L E K D T T L T E P V I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509703 483 55774 T301 Q F L E K D T T L T E P V I R
Chicken Gallus gallus XP_419432 476 55266 T295 Q F L E K D T T L T E P V I R
Frog Xenopus laevis NP_001086500 476 55192 A294 Q F L E K D T A L T E P V I R
Zebra Danio Brachydanio rerio XP_690932 478 56125 T297 Q F L E K D P T L T E V V V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651569 524 59708 F292 Q F L E K D P F L T E P V V R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780697 432 50137 H278 V K C L G L Y H A Q L A Y C V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU89 510 58740 K348 Q F V E K D C K L A D T V I R
Baker's Yeast Sacchar. cerevisiae P38903 757 85316 L529 Q F L E K D P L L T E E V V M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.6 74.3 85.1 N.A. 97.7 97.9 N.A. 95 93.2 88 80 N.A. 66.7 N.A. N.A. 68.3
Protein Similarity: 100 66.1 74.5 85.1 N.A. 98.7 98.7 N.A. 97.5 95.8 94 88.8 N.A. 78 N.A. N.A. 78.8
P-Site Identity: 100 0 20 100 N.A. 100 100 N.A. 100 100 93.3 80 N.A. 80 N.A. N.A. 0
P-Site Similarity: 100 13.3 26.6 100 N.A. 100 100 N.A. 100 100 93.3 86.6 N.A. 86.6 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 48.2 37.5 N.A.
Protein Similarity: N.A. N.A. N.A. 65.2 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 60 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 0 0 0 15 8 8 8 15 8 0 8 0 % A
% Cys: 0 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 79 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 79 0 0 0 0 0 0 72 8 0 0 0 % E
% Phe: 0 79 0 0 0 0 0 8 15 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 22 0 0 0 0 0 0 0 0 0 0 % G
% His: 15 0 0 0 0 0 0 8 0 15 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 65 0 % I
% Lys: 0 8 0 15 79 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 0 0 72 8 0 22 0 22 79 0 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 22 0 0 0 0 58 0 0 0 % P
% Gln: 79 0 0 0 0 0 0 0 0 8 0 15 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 15 0 0 0 0 50 50 0 72 0 8 0 0 0 % T
% Val: 8 0 8 0 0 0 0 0 0 0 0 8 86 22 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _