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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5A
All Species:
21.52
Human Site:
S5
Identified Species:
36.41
UniProt:
Q15172
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15172
NP_006234.1
486
56194
S5
_
_
_
M
S
S
S
S
P
P
A
G
A
A
S
Chimpanzee
Pan troglodytes
XP_001151388
673
75031
S231
A
A
E
M
S
S
S
S
P
P
A
G
A
A
S
Rhesus Macaque
Macaca mulatta
XP_001106979
628
70785
S165
A
A
E
M
S
S
S
S
P
P
A
G
A
A
S
Dog
Lupus familis
XP_547400
566
64736
P85
G
L
S
R
R
P
P
P
P
P
A
G
A
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD03
486
56328
S5
_
_
_
M
S
S
P
S
P
P
A
P
V
A
C
Rat
Rattus norvegicus
NP_001101361
486
56318
S5
_
_
_
M
S
S
P
S
P
P
A
P
V
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509703
483
55774
A5
_
_
_
M
S
A
A
A
A
A
A
G
A
I
S
Chicken
Gallus gallus
XP_419432
476
55266
I5
_
_
_
M
S
A
A
I
S
A
A
E
K
V
D
Frog
Xenopus laevis
NP_001086500
476
55192
E8
M
S
A
I
S
A
A
E
K
V
D
G
F
T
R
Zebra Danio
Brachydanio rerio
XP_690932
478
56125
S5
_
_
_
M
S
A
I
S
A
S
E
K
V
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651569
524
59708
T5
_
_
_
M
S
S
G
T
F
V
D
R
I
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780697
432
50137
S5
_
_
_
M
S
S
G
S
T
A
V
D
K
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
T43
G
A
S
T
S
K
S
T
D
N
G
A
A
K
S
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
S99
K
T
A
T
T
P
S
S
S
S
S
S
S
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.6
74.3
85.1
N.A.
97.7
97.9
N.A.
95
93.2
88
80
N.A.
66.7
N.A.
N.A.
68.3
Protein Similarity:
100
66.1
74.5
85.1
N.A.
98.7
98.7
N.A.
97.5
95.8
94
88.8
N.A.
78
N.A.
N.A.
78.8
P-Site Identity:
100
80
80
40
N.A.
66.6
66.6
N.A.
50
25
13.3
25
N.A.
25
N.A.
N.A.
33.3
P-Site Similarity:
100
80
80
46.6
N.A.
66.6
66.6
N.A.
75
41.6
33.3
33.3
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.2
37.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
49.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
22
15
0
0
29
22
8
15
22
58
8
43
43
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
15
8
0
15
15
% D
% Glu:
0
0
15
0
0
0
0
8
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% F
% Gly:
15
0
0
0
0
0
15
0
0
0
8
43
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
8
0
0
0
0
8
15
0
% I
% Lys:
8
0
0
0
0
8
0
0
8
0
0
8
15
8
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
72
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
15
22
8
43
43
0
15
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
0
8
0
8
8
% R
% Ser:
0
8
15
0
86
50
36
58
15
15
8
8
8
0
43
% S
% Thr:
0
8
0
15
8
0
0
15
8
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
15
8
0
22
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
58
58
58
0
0
0
0
0
0
0
0
0
0
0
0
% _