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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCM1 All Species: 35.15
Human Site: S1376 Identified Species: 70.3
UniProt: Q15154 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15154 NP_006188.3 2024 228485 S1376 S E T G S D F S M F E A L R D
Chimpanzee Pan troglodytes XP_001143666 2024 228648 S1376 S E T G S D F S M F E A L R D
Rhesus Macaque Macaca mulatta XP_001098130 2024 228669 S1376 S E T G S D F S M F E A L R D
Dog Lupus familis XP_856471 2034 229150 S1378 S E T G S D F S M F E A L R D
Cat Felis silvestris
Mouse Mus musculus Q9R0L6 2025 228814 S1373 S E T G S D F S M F E A L R D
Rat Rattus norvegicus NP_112338 2026 228715 S1373 S E T G S D F S M F E A L R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508627 1158 129340 S559 V F E P A D S S A V D N E L W
Chicken Gallus gallus Q8AV28 1904 212706 F1284 T G S D L S M F E A L R D T I
Frog Xenopus laevis Q9PVV4 2031 227849 T1412 S D V S M F E T L R D T I Y S
Zebra Danio Brachydanio rerio NP_001108595 2018 226056 S1395 P D V S S D F S L F E A L R E
Tiger Blowfish Takifugu rubipres NP_001027776 2075 229594 S1458 C T E A P D A S S D F S L F E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786223 2256 248984 S1617 S D A G S E F S L F E A L R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.1 91.4 N.A. 88.7 88.5 N.A. 34.1 67.5 59.4 52.6 47.8 N.A. N.A. N.A. 26.1
Protein Similarity: 100 99.5 98.5 95.1 N.A. 93.4 93.2 N.A. 43.6 77.3 73.5 67.9 64.1 N.A. N.A. N.A. 45.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 0 6.6 60 20 N.A. N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 13.3 40 80 33.3 N.A. N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 9 0 9 0 9 9 0 67 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 25 0 9 0 75 0 0 0 9 17 0 9 0 50 % D
% Glu: 0 50 17 0 0 9 9 0 9 0 67 0 9 0 25 % E
% Phe: 0 9 0 0 0 9 67 9 0 67 9 0 0 9 0 % F
% Gly: 0 9 0 59 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 0 25 0 9 0 75 9 0 % L
% Met: 0 0 0 0 9 0 9 0 50 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 9 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 9 0 67 0 % R
% Ser: 67 0 9 17 67 9 9 84 9 0 0 9 0 0 9 % S
% Thr: 9 9 50 0 0 0 0 9 0 0 0 9 0 9 0 % T
% Val: 9 0 17 0 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _