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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAP2
All Species:
18.48
Human Site:
S540
Identified Species:
50.83
UniProt:
Q15057
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15057
NP_036419.3
778
88029
S540
S
S
E
E
K
R
L
S
I
S
K
F
G
P
G
Chimpanzee
Pan troglodytes
XP_516962
964
107827
S726
S
S
E
E
K
R
L
S
I
S
K
F
G
P
G
Rhesus Macaque
Macaca mulatta
XP_001093762
932
104298
S694
S
S
E
E
K
R
L
S
I
S
K
F
G
P
G
Dog
Lupus familis
XP_545162
778
87920
S540
S
C
E
E
K
R
L
S
I
S
K
L
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQK5
770
87192
K532
Q
E
K
R
I
I
S
K
S
C
E
D
Q
R
L
Rat
Rattus norvegicus
Q5FVC7
770
87211
K532
Q
E
K
R
I
I
S
K
S
C
E
D
Q
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511466
766
86350
S528
S
H
E
E
K
R
H
S
I
S
K
T
I
P
G
Chicken
Gallus gallus
Q5ZK62
781
88436
S542
S
Q
E
E
K
R
H
S
A
P
E
K
S
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693236
749
84456
H531
K
I
M
T
L
R
K
H
D
K
R
M
Q
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
83
95.7
N.A.
95.2
94.9
N.A.
90
88
N.A.
67.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.7
83.4
97.9
N.A.
97.1
96.9
N.A.
93.9
93.7
N.A.
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
0
0
N.A.
73.3
40
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
13.3
13.3
N.A.
73.3
46.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
23
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
23
0
0
0
% D
% Glu:
0
23
67
67
0
0
0
0
0
0
34
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
34
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
45
12
56
% G
% His:
0
12
0
0
0
0
23
12
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
23
23
0
0
56
0
0
0
12
0
0
% I
% Lys:
12
0
23
0
67
0
12
23
0
12
56
12
0
0
0
% K
% Leu:
0
0
0
0
12
0
45
0
0
0
0
12
0
0
34
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
0
0
56
0
% P
% Gln:
23
12
0
0
0
0
0
0
0
0
0
0
34
0
0
% Q
% Arg:
0
0
0
23
0
78
0
0
0
0
12
0
0
23
0
% R
% Ser:
67
34
0
0
0
0
23
67
23
56
0
0
12
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _