KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCAPD2
All Species:
4.55
Human Site:
Y521
Identified Species:
12.5
UniProt:
Q15021
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15021
NP_055680.3
1401
157182
Y521
E
D
V
K
G
R
I
Y
Q
L
L
A
K
A
S
Chimpanzee
Pan troglodytes
XP_001161617
1401
157152
Y521
E
D
V
K
G
R
I
Y
Q
L
L
A
K
A
S
Rhesus Macaque
Macaca mulatta
XP_001105024
1399
157134
H519
E
E
V
K
G
R
I
H
Q
L
L
A
K
A
S
Dog
Lupus familis
XP_534910
1412
158549
R532
E
G
V
K
T
R
I
R
Q
L
L
A
K
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Z4
1392
155647
R519
E
E
V
K
G
R
I
R
Q
L
L
A
K
A
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001074331
1389
155307
G511
E
V
E
E
T
A
E
G
T
S
E
Q
I
T
G
Frog
Xenopus laevis
Q9YHY6
1364
154172
L515
Q
H
L
R
E
Q
I
L
I
L
L
R
K
T
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182856
819
91363
A36
V
Y
P
L
R
Q
V
A
D
K
I
V
A
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06156
1176
132949
N393
C
D
L
S
S
K
F
N
K
S
K
A
K
F
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.7
89
N.A.
86
N.A.
N.A.
N.A.
61.3
60.1
N.A.
N.A.
N.A.
N.A.
N.A.
25.4
Protein Similarity:
100
99.8
98.5
93.1
N.A.
91.5
N.A.
N.A.
N.A.
76.5
75.5
N.A.
N.A.
N.A.
N.A.
N.A.
39.4
P-Site Identity:
100
100
86.6
80
N.A.
86.6
N.A.
N.A.
N.A.
6.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
93.3
N.A.
N.A.
N.A.
13.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
12
0
0
0
67
12
56
12
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
34
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
67
23
12
12
12
0
12
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% F
% Gly:
0
12
0
0
45
0
0
12
0
0
0
0
0
0
12
% G
% His:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
67
0
12
0
12
0
12
0
0
% I
% Lys:
0
0
0
56
0
12
0
0
12
12
12
0
78
0
0
% K
% Leu:
0
0
23
12
0
0
0
12
0
67
67
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
23
0
0
56
0
0
12
0
0
0
% Q
% Arg:
0
0
0
12
12
56
0
23
0
0
0
12
0
0
0
% R
% Ser:
0
0
0
12
12
0
0
0
0
23
0
0
0
0
67
% S
% Thr:
0
0
0
0
23
0
0
0
12
0
0
0
0
23
12
% T
% Val:
12
12
56
0
0
0
12
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
23
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _