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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM175B
All Species:
9.39
Human Site:
Y351
Identified Species:
22.96
UniProt:
Q15018
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15018
NP_115558.3
415
46901
Y351
S
T
S
A
G
L
K
Y
P
G
S
G
A
D
L
Chimpanzee
Pan troglodytes
XP_508099
925
105851
W653
D
S
R
L
Y
A
L
W
N
R
T
A
G
D
C
Rhesus Macaque
Macaca mulatta
XP_001083977
424
47899
Y360
S
T
S
A
G
L
K
Y
P
G
S
G
A
D
L
Dog
Lupus familis
XP_535051
423
47662
Y359
S
T
S
A
G
L
K
Y
P
G
S
G
T
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCJ1
415
46924
F351
S
T
S
G
G
L
K
F
T
G
S
G
A
D
L
Rat
Rattus norvegicus
Q5I0F1
405
45671
S342
P
A
P
A
A
P
L
S
K
R
K
A
L
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHS0
405
46025
K342
T
K
L
V
T
K
R
K
V
R
V
T
T
T
G
Frog
Xenopus laevis
Q6GR31
408
45804
A344
R
Q
A
G
K
R
K
A
H
S
K
Q
L
G
K
Zebra Danio
Brachydanio rerio
Q1LVP6
391
44617
I328
I
S
T
K
L
P
Q
I
L
E
N
Q
H
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793859
236
26638
V173
T
L
S
G
V
Q
T
V
R
N
L
N
N
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
97.1
93.8
N.A.
93.4
29.6
N.A.
N.A.
32.5
33.9
31
N.A.
N.A.
N.A.
N.A.
20.9
Protein Similarity:
100
39.1
97.6
95.5
N.A.
96.3
52
N.A.
N.A.
50.8
49.8
49.8
N.A.
N.A.
N.A.
N.A.
32.5
P-Site Identity:
100
6.6
100
93.3
N.A.
80
13.3
N.A.
N.A.
0
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
93.3
N.A.
86.6
13.3
N.A.
N.A.
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
40
10
10
0
10
0
0
0
20
30
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
30
40
0
0
0
0
40
0
40
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
0
10
0
10
10
10
50
10
10
0
20
0
0
0
10
% K
% Leu:
0
10
10
10
10
40
20
0
10
0
10
0
20
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
10
10
10
0
0
% N
% Pro:
10
0
10
0
0
20
0
0
30
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
10
10
0
0
0
0
20
0
0
0
% Q
% Arg:
10
0
10
0
0
10
10
0
10
30
0
0
0
0
10
% R
% Ser:
40
20
50
0
0
0
0
10
0
10
40
0
0
10
0
% S
% Thr:
20
40
10
0
10
0
10
0
10
0
10
10
20
10
10
% T
% Val:
0
0
0
10
10
0
0
10
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _