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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM175B
All Species:
9.09
Human Site:
S387
Identified Species:
22.22
UniProt:
Q15018
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15018
NP_115558.3
415
46901
S387
L
I
D
P
T
E
P
S
N
S
E
Y
S
H
S
Chimpanzee
Pan troglodytes
XP_508099
925
105851
D689
A
L
H
D
S
L
H
D
C
S
H
W
F
Y
T
Rhesus Macaque
Macaca mulatta
XP_001083977
424
47899
S396
L
I
D
P
T
E
P
S
N
S
E
Y
S
H
S
Dog
Lupus familis
XP_535051
423
47662
S395
L
I
D
P
T
E
P
S
N
S
E
Y
S
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCJ1
415
46924
P387
L
I
D
P
A
E
S
P
H
S
E
Y
S
H
S
Rat
Rattus norvegicus
Q5I0F1
405
45671
K378
F
R
G
S
H
Q
D
K
A
S
S
S
S
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHS0
405
46025
L378
D
C
N
Q
E
T
K
L
A
L
S
S
A
E
T
Frog
Xenopus laevis
Q6GR31
408
45804
L380
E
S
S
D
S
E
K
L
L
C
T
S
G
T
E
Zebra Danio
Brachydanio rerio
Q1LVP6
391
44617
E364
K
R
K
R
K
T
R
E
V
S
E
S
A
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793859
236
26638
R209
G
Q
E
V
S
E
L
R
R
R
A
Q
R
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
97.1
93.8
N.A.
93.4
29.6
N.A.
N.A.
32.5
33.9
31
N.A.
N.A.
N.A.
N.A.
20.9
Protein Similarity:
100
39.1
97.6
95.5
N.A.
96.3
52
N.A.
N.A.
50.8
49.8
49.8
N.A.
N.A.
N.A.
N.A.
32.5
P-Site Identity:
100
6.6
100
100
N.A.
73.3
13.3
N.A.
N.A.
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
40
100
100
N.A.
80
20
N.A.
N.A.
20
13.3
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
20
0
10
0
20
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% C
% Asp:
10
0
40
20
0
0
10
10
0
0
0
0
0
0
10
% D
% Glu:
10
0
10
0
10
60
0
10
0
0
50
0
0
10
20
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
10
0
10
0
10
0
10
0
10
0
0
40
0
% H
% Ile:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
0
10
0
20
10
0
0
0
0
0
0
0
% K
% Leu:
40
10
0
0
0
10
10
20
10
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
30
0
0
0
0
0
0
% N
% Pro:
0
0
0
40
0
0
30
10
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
10
0
10
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
20
0
10
0
0
10
10
10
10
0
0
10
0
10
% R
% Ser:
0
10
10
10
30
0
10
30
0
70
20
40
50
10
40
% S
% Thr:
0
0
0
0
30
20
0
0
0
0
10
0
0
10
20
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
40
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _